Department of Neurosurgery, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.
Department of Emergency Trauma Centre, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.
J Int Med Res. 2020 Oct;48(10):300060520952266. doi: 10.1177/0300060520952266.
Meningioma of the spinal canal is very rare. Clear cell meningioma (CCM) with special histological features occurs more commonly in the spinal cord. A review of the published English-language literature identified 40 reported cases of children with intraspinal CCM and this current report presents an additional case of a 3-year-old child with confirmed lumbar CCM. The current case underwent gross total resection of the CCM. At 9 months after the operation, lumbar magnetic resonance imaging was undertaken and confirmed the absence of tumour recurrence. The child was able to walk normally again. During this period, the child did not receive adjuvant treatments such as radiotherapy and chemotherapy. An evaluation of the 41 cases demonstrated the following: (i) there was no significant difference between the recurrence rate of females and males; (ii) there was a significant difference in the recurrence rate based on the extent of resection (gross total resection versus partial resection); (iii) the recurrence rate in patients where the number of involved segments ≥3 levels was significantly higher than that in patients where the number of involved segments was 1-2 levels. For children with CCM, complete surgical resection might be an important characteristic for predicting the risk of the recurrence of CCM.
椎管内脑膜瘤非常罕见。具有特殊组织学特征的透明细胞脑膜瘤（CCM）更常见于脊髓。对已发表的英文文献进行回顾，共确定了 40 例儿童椎管内 CCM 的病例，本报告介绍了另 1 例经证实的 3 岁儿童腰椎 CCM 病例。该患儿行 CCM 全切除。术后 9 个月，行腰椎磁共振成像检查，证实肿瘤无复发。患儿可再次正常行走。在此期间，患儿未接受放疗和化疗等辅助治疗。对 41 例病例的评估表明：（i）女性和男性的复发率无显著差异；（ii）根据切除范围（全切除与部分切除），复发率存在显著差异；（iii）累及节段数≥3 个水平的患者复发率明显高于累及节段数为 1-2 个水平的患者。对于 CCM 患儿，完全手术切除可能是预测 CCM 复发风险的一个重要特征。
