Janner A
Institute for Theoretical Physics, Radboud University, Toernooiveld, 6525 ED Nijmegen, The Netherlands.
Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):247-55. doi: 10.1107/S090744490403269X. Epub 2005 Feb 24.
The geometry of the molecular envelope and channel in axial-symmetric proteins is investigated in order to test the validity of rules deduced previously from several other biomacromolecules. Again, molecular forms with remarkable geometric properties are found. In particular, for order of rotation N = 2, 3, 4, 6 the molecular forms encapsulating the C(alpha) backbone of the protein have vertices at lattice points and therefore integral indices. These lattices are characterized by a height-to-width axial ratio that reduces the number of free parameters and enhances the symmetry.
为了检验先前从其他几种生物大分子推导出来的规则的有效性，对轴对称蛋白质中分子包膜和通道的几何结构进行了研究。再次发现具有显著几何特性的分子形式。特别是，对于旋转阶数N = 2、3、4、6，包裹蛋白质Cα主链的分子形式在晶格点处有顶点，因此具有整数指数。这些晶格的特征是高宽轴比，这减少了自由参数的数量并增强了对称性。
