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新生儿不对称哭脸综合征:对一个老问题的新审视。

Neonatal asymmetric crying facies: a new look at an old problem.

作者信息

Sapin Samuel O, Miller Alvin A, Bass Harold N

机构信息

David Geffen School of Medicine at UCLA, Los Angeles, California 91403, USA.

出版信息

Clin Pediatr (Phila). 2005 Mar;44(2):109-19. doi: 10.1177/000992280504400202.

DOI:10.1177/000992280504400202
PMID:15735828
Abstract

Neonatal asymmetric crying facies, described 75 years ago, is a clinical phenotype resembling unilateral partial peripheral facial nerve paralysis, with an incidence of approximately 1 per 160 live births. The cause is either facial nerve compression or faulty facial muscle and/or nerve development. Spontaneous resolution is expected with the former, but not necessarily with the latter etiology. Approximately 10% of the developmental cases have associated major malformations. Mandibular asymmetry and maxillary-mandibular asynclitism (non-parallelism of the gums) are frequently overlooked visual clues to nerve compression. Ultrasound imaging of facial muscles and electrodiagnostic testing may be useful for differential diagnosis and management.

摘要

75年前被描述的新生儿不对称哭泣面容,是一种类似于单侧部分周围性面神经麻痹的临床表型,发病率约为每160例活产中有1例。病因要么是面神经受压,要么是面部肌肉和/或神经发育异常。前者有望自发缓解,但后者病因则不一定。约10%的发育性病例伴有严重畸形。下颌不对称和上颌-下颌不同步(牙龈不平行)是神经受压时经常被忽视的视觉线索。面部肌肉超声成像和电诊断测试可能有助于鉴别诊断和处理。

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1
Neonatal asymmetric crying facies: a new look at an old problem.新生儿不对称哭脸综合征:对一个老问题的新审视。
Clin Pediatr (Phila). 2005 Mar;44(2):109-19. doi: 10.1177/000992280504400202.
2
Asymmetric crying facies with a couple of primary mandibular central incisor and 22q11 deletion.不对称哭泣面容伴几颗下颌乳中切牙及22q11缺失。
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[An infant with an asymmetric mouth when crying or laughing].一名在哭笑时嘴巴不对称的婴儿。
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[Asymmetric crying facies syndrome].[不对称哭泣面容综合征]
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Familial asymmetric crying facies. Its occurrence secondary to hypoplasia of the anguli oris depressor muscles.家族性不对称哭泣面容。其发生继发于口角降肌发育不全。
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Asymmetric crying facies: an alternative interpretation.不对称哭泣面容:一种不同的解释。
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Asymmetric crying facies in an elderly, when a facial asymmetry is not a facial paralysis but a marker of possible congenital malformations: case report and review of the literature.老年患者的不对称哭泣面容,当面部不对称并非面神经麻痹而是可能的先天性畸形标志时:病例报告及文献复习
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Asymmetric crying facies and congenital eye defects in an infant.一名婴儿的不对称哭泣面容与先天性眼部缺陷。
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Associated anomalies in asymmetric crying facies and 22q11 deletion.不对称哭泣面容与22q11缺失相关的异常情况。
Genet Couns. 2003;14(3):325-30.

引用本文的文献

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A Rare Case of Unilateral Congenital Asymmetric Crying Facies in a Neonate: Case Report.新生儿单侧先天性不对称哭泣面容1例:病例报告
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2
The Manifestation of Congenital Hypoplasia of the Depressor Anguli Oris: A Case Report of Asymmetric Crying Facies.降口角肌先天性发育不全的表现:一例不对称哭泣面容的病例报告
Cureus. 2025 Feb 1;17(2):e78352. doi: 10.7759/cureus.78352. eCollection 2025 Feb.
3
Genetic Testing in Craniofacial Care: Development of Algorithms for Testing Patients with Orofacial Clefting, Branchial Arch Anomalies, and Craniosynostosis.
颅面护理中的基因检测:用于检测患有口面部裂、鳃弓异常和颅缝早闭患者的检测算法的开发。
Cleft Palate Craniofac J. 2025 Oct;62(10):1764-1773. doi: 10.1177/10556656241276857. Epub 2024 Aug 18.
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Congenital unilateral lower lip palsy: a case-based review.先天性单侧下唇麻痹:基于病例的综述
Childs Nerv Syst. 2023 Jan;39(1):35-40. doi: 10.1007/s00381-022-05695-1. Epub 2022 Oct 6.
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Facial Asymmetry in a Newly Born Baby: Diagnostic Challenge!新生儿面部不对称:诊断挑战!
Clin Med Insights Case Rep. 2022 Mar 28;15:11795476221088487. doi: 10.1177/11795476221088487. eCollection 2022.
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Hypoplasia of Depressor Angularis Oris in a Male Neonate Associated with Cephalohematoma.一名男性新生儿口轮匝肌发育不全与头颅血肿相关
Cureus. 2020 Mar 8;12(3):e7213. doi: 10.7759/cureus.7213.
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Congenital unilateral hypoplasia of depressor anguli oris muscle in adult.成人先天性单侧降口角肌发育不全
Arch Craniofac Surg. 2019 Aug;20(4):265-269. doi: 10.7181/acfs.2019.00297. Epub 2019 Aug 20.
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[Asymmetric crying facies and vocal cord paralysis accompanied by congenital heart disease in an infant].[一名婴儿出现不对称哭泣面容及声带麻痹并伴有先天性心脏病]
Zhongguo Dang Dai Er Ke Za Zhi. 2019 Jun;21(6):585-588. doi: 10.7499/j.issn.1008-8830.2019.06.016.
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Congenital asymmetric crying facies syndrome: A case report.先天性不对称哭脸综合征:一例报告。
Medicine (Baltimore). 2018 Aug;97(31):e11403. doi: 10.1097/MD.0000000000011403.
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Facial Asymmetry in a Crying Newborn: A Comparison of Two Cases and Review of Literature.哭闹新生儿的面部不对称:两例病例比较及文献综述
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