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印度孟买一家三级护理中心耐多药结核分枝杆菌分离株中北京基因型的高发生率。

High incidence of the Beijing genotype among multidrug-resistant isolates of Mycobacterium tuberculosis in a tertiary care center in Mumbai, India.

作者信息

Almeida Deepak, Rodrigues Camilla, Ashavaid Tester F, Lalvani Ajit, Udwadia Zarir F, Mehta Ajita

机构信息

Research Labs, P. D. Hinduja National Hospital and Medical Research Centre, Mahim, Mumbai, India.

出版信息

Clin Infect Dis. 2005 Mar 15;40(6):881-6. doi: 10.1086/427940. Epub 2005 Feb 18.

Abstract

We report a high frequency (35%) of the Beijing genotype among multidrug-resistant isolates recovered in and around Mumbai, India. Further restriction fragment-length polymorphism typing showed that these strains were closely related. We also report a high frequency of the Delhi genotype (31% of isolates). Our data indicate considerable ongoing transmission of multidrug-resistant Mycobacterium tuberculosis strains of the Beijing genotype in Mumbai.

摘要

我们报告了在印度孟买及其周边地区分离出的耐多药菌株中北京基因型的高频率(35%)。进一步的限制性片段长度多态性分型显示这些菌株密切相关。我们还报告了德里基因型的高频率(占分离株的31%)。我们的数据表明,孟买存在北京基因型耐多药结核分枝杆菌菌株的大量持续传播。

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