Jørgensen Marit E
Steno Diabetes Centre, Gentofte, Denmark.
Int J Circumpolar Health. 2004;63 Suppl 2:77-9. doi: 10.3402/ijch.v63i0.17818.
[corrected] Obesity and central fat pattern are associated with several cardiovascular risk factors incluy ding insulin resistance, glucose intolerance, hypertension and dyslipidemia in most populations. The study aims to assess the occurrence and metabolic correlates of obesity among Greenlanders and Danes.
From 1999 to 2001, 917 adult Inuit participated in a health survey in Greenland. The examination included an oral glucose tolerance test. Body Mass Index, waist circumference, and blood pressure were measured. P-glucose, s-insulin, and lipids were measured. Data from the Danish study 'Inter99' (n=5606) conducted in 1999-2000 were used for comparison.
Compared with the Inter99 population, a larger proportion of Inuit women were centrally obese (58.1% vs.17.8%, p<0.001) and central obesity was present in 15.9% of Inuit men vs. 8.3% of the Danish men (p<0.001). At any given level of obesity the Inuit had lower levels of 2-hour glucose and insulin, blood pressure, triglyceride, and higher levels of HDL cholesterol than the Danish participants. Fasting glucose and fasting insulin levels within obesity categories were not different in the two populations.
Central fat pattern and obesity are more prevalent among the Inuit, but the obesity observed among the Inuit is not associated with the same degree of metabolic disturbances as in a general Danish population.
肥胖和中心性脂肪分布模式与大多数人群中的多种心血管危险因素相关，包括胰岛素抵抗、葡萄糖耐量异常、高血压和血脂异常。本研究旨在评估格陵兰人和丹麦人中肥胖的发生率及其代谢相关性。
1999年至2001年，917名成年因纽特人参加了格陵兰的一项健康调查。检查包括口服葡萄糖耐量试验。测量了体重指数、腰围和血压。检测了空腹血糖、空腹胰岛素和血脂。将1999年至2000年丹麦开展的“Inter99”研究（n = 5606）的数据用于比较。
与Inter99人群相比，因纽特女性中心性肥胖的比例更高（58.1%对17.8%，p<0.001），15.9%的因纽特男性存在中心性肥胖，而丹麦男性的这一比例为8.3%（p<0.001）。在任何给定的肥胖水平下，因纽特人的2小时血糖、胰岛素、血压、甘油三酯水平较低，高密度脂蛋白胆固醇水平较高。两个群体中肥胖类别内的空腹血糖和空腹胰岛素水平没有差异。
中心性脂肪分布模式和肥胖在因纽特人中更为普遍，但因纽特人中观察到的肥胖与丹麦普通人群相比，代谢紊乱程度不同。
