Causse Xavier, D'Alteroche Louis, Si Ahmed Si Nafa, Giraudeau Bruno, Metman Etienne-Henri
Service d'Hépato-gastroentérologie, CHR La Source, BP 6709, 45067 Orléans Cedex 2, France.
Gastroenterol Clin Biol. 2005 Jan;29(1):63-8.
The survey conducted in the Provence-Alpes-Cote d'Azur region in France in 1999 showed that 38% of patients infected with the hepatitis C virus (HCV) receiving interferon injections in their home were aware of the recommendations concerning the disposal of injection material and that 41% of the needles were discarded with household waste after use. The purpose of our study conducted in the Centre region of France was to ascertain how injection material used by HCV-positive patients for interferon treatment are disposed of in comparison with material used by patients injecting insulin for insulin-dependent diabetes mellitus (IDDM) or low-molecular-weight heparin (LMWH) for thromboembolism.
A questionnaire to be completed by patients was proposed to HCV-positive patients attending hepatogastroenterology clinics in the Centre region hepatitis C network for therapeutic follow-up (N=113 patients) between October 2001-January 2002. The same questionnaire was proposed to patients attending follow-up consultations for insulin-dependent diabetes mellitus (N=85 patients) or thromboembolism (N=23 patients) between March-June 2002.
Significantly more patients stated they were aware of recommendations for disposal of injection material in the HCV group (89%) than in the IDDM (67%) or LMWH (26%) groups (P<0.01). Injection material was discarded with household waste less often by patients in the HCV group (6%) than in the IDDM (32%) or LMWH (29%) groups (P<0.001) and more often collected in a safety box prior to incineration (73% in the HCV group versus 63% and 14% in the IDDM and LMWH groups respectively). The safety box was discarded with household garbage more often by patients in the IDDM (54%) or LMWH (50%) groups than in the HCV group (0%) (P<0.001). Equivalent proportions of the patients said they recapped the needle after use (HCV 83%; IDDM 93%; LMWH 84%).
Information concerning use of safety boxes for disposal of injection material should be provided to patients in order to comply with regulatory recommendations on proper disposal of used injection material. Moreover, the habit of recapping needles (89% of all patients in this study) is still widespread.
1999年在法国普罗旺斯-阿尔卑斯-蓝色海岸地区进行的一项调查显示，在家中接受干扰素注射的丙型肝炎病毒（HCV）感染患者中，38%知晓有关注射材料处置的建议，且41%的针头在使用后随生活垃圾丢弃。我们在法国中央地区开展研究的目的是，确定HCV阳性患者用于干扰素治疗的注射材料的处置方式，与注射胰岛素治疗胰岛素依赖型糖尿病（IDDM）或注射低分子量肝素（LMWH）治疗血栓栓塞的患者所使用材料的处置方式相比有何不同。
2001年10月至2002年1月期间，向中央地区丙型肝炎网络肝病胃肠病诊所接受治疗随访的HCV阳性患者（N = 113例患者）发放了一份由患者填写的问卷。2002年3月至6月期间，向接受胰岛素依赖型糖尿病随访咨询的患者（N = 85例患者）或血栓栓塞随访咨询的患者（N = 23例患者）发放了相同问卷。
HCV组中表示知晓注射材料处置建议的患者（89%）显著多于IDDM组（67%）或LMWH组（26%）（P < 0.01）。HCV组患者将注射材料随生活垃圾丢弃的情况（6%）少于IDDM组（32%）或LMWH组（29%）（P < 0.001），且在焚烧前更多地收集在安全盒中（HCV组为73%，而IDDM组和LMWH组分别为63%和14%）。IDDM组（54%）或LMWH组（50%）患者将安全盒随生活垃圾丢弃的情况多于HCV组（0%）（P < 0.001）。各组中表示使用后重新套上针头的患者比例相当（HCV组83%；IDDM组93%；LMWH组84%）。
应向患者提供有关使用安全盒处置注射材料的信息，以符合关于正确处置用过的注射材料的监管建议。此外，重新套上针头的习惯（本研究中所有患者的89%）仍然很普遍。
