Murofushi Toshihisa, Takai Yoshinari, Iwasaki Shinichi, Matsuzaki Masaki
Department of Otolaryngology, Tokyo Postal Services Agency Hospital, 2-14-23 Fujimi Chiyoda-ku, 102-8798, Tokyo, Japan.
Eur Arch Otorhinolaryngol. 2005 Oct;262(10):864-7. doi: 10.1007/s00405-004-0913-y. Epub 2005 Mar 1.
To reduce the testing time of vestibular evoked myogenic potentials (VEMP) and the physical efforts of subjects, we studied if VEMP recording by binaural simultaneous stimulation in patients with vestibulo-cochlear disorders can be applicable as a screening test. Twenty-eight patients with vestibulo-cochlear disorders (12 men and 16 women, 22 to 77 years of age) were enrolled in this study. Patients were presented with binaural or monaural click (95 dBnHL) stimulation to record VEMPs. Their VEMP responses to binaural simultaneous stimulation were compared with those of monaural individual stimulation. Twenty-six of the 28 patients (93%) showed the same results in binaural simultaneous stimulation as in monaural individual stimulation. Amplitudes of p13-n23 to binaural simultaneous stimulation showed significant correlation to those of monaural individual stimulation ( r =0.774, P <0.0001 t -test). Peak latencies of p13 and n23 of binaural simultaneous stimulation also showed significant correlation to those of monaural individual stimulation (p13: r =0.684, P <0.0001 t -test, n23: r =0.657, P <0.0001 t -test). The binaural simultaneous stimulation method for VEMP recording is applicable for patients with vestibulo-cochlear disorders as a screening test in the clinic.
为了减少前庭诱发肌源性电位（VEMP）的检测时间以及受试者的体力消耗，我们研究了双耳同时刺激记录VEMP在患有前庭蜗神经疾病的患者中是否可作为一种筛查测试。本研究纳入了28例患有前庭蜗神经疾病的患者（12名男性和16名女性，年龄在22至77岁之间）。对患者进行双耳或单耳短声（95 dBnHL）刺激以记录VEMP。将他们对双耳同时刺激的VEMP反应与单耳单独刺激的反应进行比较。28例患者中有26例（93%）在双耳同时刺激和单耳单独刺激中的结果相同。双耳同时刺激时p13 - n23的振幅与单耳单独刺激时的振幅呈显著相关性（r = 0.774，t检验，P < 0.0001）。双耳同时刺激时p13和n23的峰潜伏期与单耳单独刺激时的峰潜伏期也呈显著相关性（p13：r = 0.684，t检验，P < 0.0001；n23：r = 0.657，t检验，P < 0.0001）。用于记录VEMP的双耳同时刺激方法适用于患有前庭蜗神经疾病的患者，可作为临床筛查测试。
