同时记录颈和眼前庭诱发肌源性电位。

Simultaneous recording of cervical and ocular vestibular-evoked myogenic potentials.

机构信息

From the Department of Neurology (S.-Y.O., H.-J.S.), Chonbuk National University School of Medicine; Research Institute of Clinical Medicine (S.-Y.O., H.-J.S.), Chonbuk National University-Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea; Department of Neurology (S.-Y.O., M.E., P.z.E., M.D.) and German Center for Vertigo and Balance Disorders (R.B., M.D.), University Hospital, and Graduate School of Systemic Neuroscience (R.B., M.E., P.z.E., M.D.), Ludwig-Maximilians-University; Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; and Department of Neurology (J.-S.K.), Seoul National University School of Medicine, Korea.

出版信息

Neurology. 2018 Jan 16;90(3):e230-e238. doi: 10.1212/WNL.0000000000004835. Epub 2017 Dec 20.

DOI:10.1212/WNL.0000000000004835

PMID:29263227

Abstract

OBJECTIVE

To increase clinical application of vestibular-evoked myogenic potentials (VEMPs) by reducing the testing time by evaluating whether a simultaneous recording of ocular and cervical VEMPs can be achieved without a loss in diagnostic sensitivity and specificity.

METHODS

Simultaneous recording of ocular and cervical VEMPs on each side during monaural stimulation, bilateral simultaneous recording of ocular VEMPs and cervical VEMPs during binaural stimulation, and conventional sequential recording of ocular and cervical VEMPs on each side using air-conducted sound (500 Hz, 5-millisecond tone burst) were compared in 40 healthy participants (HPs) and 20 patients with acute vestibular neuritis.

RESULTS

Either simultaneous recording during monaural and binaural stimulation effectively reduced the recording time by ≈55% of that for conventional sequential recordings in both the HP and patient groups. The simultaneous recording with monaural stimulation resulted in latencies and thresholds of both VEMPs and the amplitude of cervical VEMPs similar to those found during the conventional recordings but larger ocular VEMP amplitudes (156%) in both groups. In contrast, compared to the conventional recording, simultaneous recording of each VEMP during binaural stimulation showed reduced amplitudes (31%) and increased thresholds for cervical VEMPs in both groups.

CONCLUSIONS

The results of simultaneous recording of cervical and ocular VEMPs during monaural stimulation were comparable to those obtained from the conventional recording while reducing the time to record both VEMPs on each side.

CLINICALTRIALSGOV IDENTIFIER

NCT03049683.

摘要

目的

通过评估单侧刺激时同时记录眼肌和颈肌前庭诱发肌源性电位（VEMPs）是否可以在不损失诊断敏感性和特异性的情况下减少测试时间，从而增加 VEMPs 的临床应用。

方法

在 40 名健康参与者（HP）和 20 名急性前庭神经炎患者中，比较了单侧刺激时同时记录眼肌和颈肌 VEMPs、双侧刺激时同时记录眼肌和颈肌 VEMPs以及常规顺序记录单侧刺激时的眼肌和颈肌 VEMPs（500 Hz，5 毫秒短声）。

结果

无论是单侧刺激还是双侧刺激的同时记录，都能有效地将 HP 和患者组的记录时间分别缩短约 55%。与常规记录相比，单侧刺激的同时记录导致 VEMP 的潜伏期和阈值以及颈肌 VEMP 的振幅与常规记录相似，但两组的眼肌 VEMP 振幅更大（156%）。相比之下，与常规记录相比，双侧刺激时同时记录每个 VEMP 导致颈肌 VEMP 的振幅减小（31%）和阈值增加，在两组中均如此。