Tom L W, Anderson G J, Womer R B, Wetmore R F, Handler S D, Potsic W P, Goldwein J W
Department of Otolaryngology, Children's Hospital of Philadelphia, PA 19104.
Laryngoscope. 1992 May;102(5):509-14. doi: 10.1288/00005537-199205000-00007.
A retrospective analysis identified 29 children with nasopharyngeal malignancies who were evaluated at the Children's Hospital of Philadelphia from 1970 through 1989. Rhabdomyosarcoma (15) and carcinoma (9) were the most common tumor types, and there were distinct differences in the clinical presentations of these two malignancies. Patients with rhabdomyosarcoma were generally younger than those with carcinoma and enjoyed longer survival. Six (67%) of the children with carcinoma were black; all of the patients with rhabdomyosarcoma were white. Patients with carcinoma were also more likely to present with cervical metastases. The presentation, evaluation, and methods of treatment for pediatric nasopharyngeal malignancies are discussed.
一项回顾性分析确定了1970年至1989年在费城儿童医院接受评估的29例鼻咽恶性肿瘤患儿。横纹肌肉瘤(15例)和癌(9例)是最常见的肿瘤类型,这两种恶性肿瘤的临床表现存在明显差异。横纹肌肉瘤患者通常比癌患者年龄小,生存期更长。癌患儿中有6例(67%)为黑人;所有横纹肌肉瘤患者均为白人。癌患者也更易出现颈部转移。本文讨论了儿童鼻咽恶性肿瘤的表现、评估和治疗方法。