Shireman Theresa I, Reichard Amanda, Rigler Sally K
University of Kansas School of Pharmacy and Landon Center on Aging, Lawrence, Kansas 66045-7582, USA.
J Child Adolesc Psychopharmacol. 2005 Feb;15(1):107-15. doi: 10.1089/cap.2005.15.107.
Knowledge of current patterns of psychotropic medication use by disabled youths is an important starting point for targeting future efforts to improve prescribing practices. This study provides a retrospective, descriptive analysis of the prevalence and patterns of psychotropic medication among 1022 Kansas Medicaid youths in 2001 who were enrolled with either Supplemental Security Income (SSI) or Medically Needy benefits and who were having clearly defined mental and neurological disabilities. Rates of psychotropic medication use were generally higher for the Medically Needy than for the SSI youths: Central nervous system (CNS) stimulants (24.6% versus 20.0%), antidepressants (30.9% versus 13.7%), anticonvulsants (22.0% versus 13.9%), and antipsychotics (23.3% versus 11.5%). Use of the four major drug classes varied among children with attention-deficit/hyperactivity disorder (ADHD) and disruptive disorders, pervasive developmental disabilities, mental retardation (MR) and learning disabilities, mood and anxiety disorders, and adjustment disorders. Future work should explore the appropriateness and effectiveness of these medications within specifically targeted subgroups.
了解残疾青少年目前使用精神药物的模式是确定未来改进处方实践工作重点的重要起点。本研究对2001年堪萨斯州医疗补助计划中的1022名青少年进行了回顾性描述性分析,这些青少年参加了补充保障收入(SSI)计划或医疗贫困补助计划,且患有明确的精神和神经残疾。医疗贫困青少年使用精神药物的比例总体上高于SSI青少年:中枢神经系统(CNS)兴奋剂(24.6%对20.0%)、抗抑郁药(30.9%对13.7%)、抗惊厥药(22.0%对13.9%)和抗精神病药(23.3%对11.5%)。在患有注意力缺陷/多动障碍(ADHD)和破坏性行为障碍、广泛性发育障碍、智力障碍(MR)和学习障碍、情绪和焦虑障碍以及适应障碍的儿童中,这四类主要药物的使用情况各不相同。未来的工作应探索这些药物在特定目标亚组中的适用性和有效性。