以腹部和侧腹疼痛为初始表现的甲状腺乳头状癌。
Papillary thyroid cancer with an initial presentation of abdominal and flank pain.
作者信息
Ruggiero Francis P, Frauenhoffer Elizabeth E, Stack Brendan C
机构信息
Division of Otolaryngol Head Neck Surg., Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
出版信息
Am J Otolaryngol. 2005 Mar-Apr;26(2):142-5. doi: 10.1016/j.amjoto.2004.08.008.
PURPOSE
Well-differentiated thyroid cancer typically presents as a thyroid mass. Common sites of metastases upon presentation include cervical lymph nodes, lung, and bone. Well-differentiated thyroid cancer with clinically apparent kidney metastases is rare, with fewer than 20 cases reported in the literature. In the vast majority of these cases, the patients had known thyroid neoplasms at the time the renal metastases were identified. We report a case of papillary thyroid carcinoma that presented with abdominal pain in a 25-year-old woman with no previous history of thyroid disease.
STUDY DESIGN
This study is a case report.
RESULTS
The patient underwent radical nephrectomy for a right renal mass, which was diagnosed as papillary thyroid carcinoma follicular variant. During subsequent evaluation, metastatic disease was also identified in the patient's lungs. The patient was treated with total thyroidectomy and iodine 131.
CONCLUSIONS
Papillary cancer, which ordinarily behaves in an indolent manner, can have unusual presentation, including disseminated metastasis on presentation. Renal metastases are extremely rare.
目的
高分化甲状腺癌通常表现为甲状腺肿块。初诊时常见的转移部位包括颈部淋巴结、肺和骨。临床上出现明显肾转移的高分化甲状腺癌很罕见,文献报道少于20例。在绝大多数此类病例中,患者在发现肾转移时已有甲状腺肿瘤。我们报告一例25岁女性乳头状甲状腺癌病例,该患者此前无甲状腺疾病史,以腹痛就诊。
研究设计
本研究为病例报告。
结果
患者因右肾肿块接受根治性肾切除术,术后诊断为滤泡状变异型乳头状甲状腺癌。在随后的评估中,还发现患者肺部有转移性疾病。患者接受了甲状腺全切术和碘131治疗。
结论
乳头状癌通常生长缓慢,但可能有不寻常的表现,包括初诊时就出现广泛转移。肾转移极为罕见。