Gao Yunfei, Deng Weiye, Chen Yanfeng, Fan Yunping, Guo Zhuming
Department of Otolaryngology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong 519020, P.R. China.
Division of Epidemiology, Human Genetics and Environmental Sciences (EHGES), The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA.
Mol Clin Oncol. 2017 Jun;6(6):821-824. doi: 10.3892/mco.2017.1243. Epub 2017 May 8.
Distant metastasis of thyroid carcinoma is rare, and it occurs particularly rarely in renal regions, which represent ~3% of all thyroid distant metastases, with fewer than 30 single case study reports existing in the literature. The present study (and subsequent literature review) of papillary thyroid carcinoma (PTC) reports the case of a 53-year-old male patient who presented with a left renal mass and who had no previous history of thyroid disease. Following renal and thyroid surgery, postoperative pathology confirmed the case to be a follicular variant of PTC, accompanied by renal metastasis. The patient exhibited brain metastasis during a later follow-up. In conclusion, thyroid metastases to the renal site are extremely rare events, particularly for men who present initially with renal neoplasms, which may easily be misdiagnosed as renal cell carcinoma. PTC tends to have a good prognosis; however, when it is accompanied by distant metastasis, the prognosis becomes less favorable.
甲状腺癌的远处转移很少见，在肾区发生的情况尤为罕见，肾区转移约占所有甲状腺远处转移的3%，文献中仅有不到30例单病例研究报告。本项关于甲状腺乳头状癌（PTC）的研究（以及后续文献综述）报告了一例53岁男性患者，该患者出现左肾肿物，既往无甲状腺疾病史。经过肾脏和甲状腺手术后，术后病理证实该病例为PTC滤泡变体，伴有肾转移。该患者在随后的随访中出现了脑转移。总之，甲状腺转移至肾脏部位是极其罕见的事件，特别是对于最初表现为肾肿瘤的男性患者，这类患者很容易被误诊为肾细胞癌。PTC通常预后良好；然而，当伴有远处转移时，预后则较差。
