Oei Adam, Hartley Laurence R
Murdoch University, School of Psychology, Division of Health Sciences, Murdoch, Australia.
Hum Psychopharmacol. 2005 Apr;20(3):193-202. doi: 10.1002/hup.681.
The present study contrasted caffeine's effects on individuals who expect caffeine to stimulate them and those who do not. Secondly, whether a message that caffeine rather than placebo was administered would also affect these two groups of subjects differently was investigated. The study was conducted single-blind in a 2x2x2 mixed design. The between subjects factor was whether they expected caffeine to stimulate them (E+) or not (E-) according to their self reports obtained before the experiment began. The within subjects factors were message (told caffeine vs told placebo) and beverage type (given caffeine vs placebo). Sixteen subjects in each group (n=32) performed on signal detection, memory scanning and delayed free recall tasks following ingestion of either caffeinated or decaffeinated coffee on two sessions each, a total of four experimental sessions. On each session, subjects were given a message regarding their drink (told caffeine vs told placebo). However, on two sessions there was a mismatch between the message and drink given. For signal detection, performance under caffeine was better than placebo in the E+ but not the E- group. However, subjects in the E+ group did not benefit more than the E- group in either message condition. On memory scanning, detections and false alarms did not differ for either beverage, nor was there a differential finding in the E+ and E- groups. However, reaction time under caffeine condition was shorter. No effects of message were found. Caffeine and message also did not have any effect on performance on the delayed free recall task. The hypothesis that caffeine and message would affect E+ and E- subjects differentially was partly supported.
本研究对比了咖啡因对预期咖啡因会刺激自己的个体和不预期的个体的影响。其次,研究了告知受试者服用的是咖啡因而非安慰剂这一信息是否也会对这两组受试者产生不同影响。该研究采用2x2x2混合设计,以单盲方式进行。受试者间因素是根据实验开始前的自我报告,他们是否预期咖啡因会刺激自己(预期组,E+)或不预期(非预期组,E-)。受试者内因素是信息(告知服用咖啡因与告知服用安慰剂)和饮料类型(给予咖啡因与给予安慰剂)。每组16名受试者(n = 32)在两次实验中分别摄入含咖啡因或不含咖啡因的咖啡后,进行信号检测、记忆扫描和延迟自由回忆任务,总共四个实验环节。在每个环节,都会告知受试者其饮用的饮料信息(告知服用咖啡因与告知服用安慰剂)。然而,在两个环节中,所给信息与饮料存在不匹配的情况。在信号检测方面,咖啡因条件下预期组的表现优于安慰剂组,但非预期组并非如此。然而,在两种信息条件下,预期组受试者并未比非预期组受试者受益更多。在记忆扫描方面,两种饮料的检测和错误警报没有差异,预期组和非预期组也没有差异发现。然而,咖啡因条件下的反应时间更短。未发现信息有任何影响。咖啡因和信息对延迟自由回忆任务的表现也没有任何影响。咖啡因和信息会对预期组和非预期组受试者产生不同影响这一假设得到了部分支持。