Hypomelanosis of Ito: diagnostic criteria and report of 41 cases.
作者信息
Ruiz-Maldonado R, Toussaint S, Tamayo L, Laterza A, del Castillo V
机构信息
Department of Dermatology, National Institute of Pediatrics, Mexico City, Mexico.
出版信息
Pediatr Dermatol. 1992 Mar;9(1):1-10. doi: 10.1111/j.1525-1470.1992.tb00317.x.
Abstract
We conducted a 20-year prospective review of 41 pediatric patients with a diagnosis of hypomelanosis of Ito. No evidence pointed to hereditary transmission of the disease. Associated extracutaneous pathology was mainly of the nervous and musculoskeletal systems. Three of 19 patients had chromosomal anomalies. Hypomelanosis of Ito is a clinically well-characterized syndrome in which chromosomal instability may be a component. Criteria for its presumptive and definitive diagnosis are proposed.
摘要
Zotero 插件