Facius Axel, Englbrecht Claudia, Birzele Fabian, Groscurth Andreas, Benjamin Schmidt, Wanka Steffi, Mewes Werner
Institute for Bioinformatics, GSF Research Center, D-85764 Neuherberg, Germany.
Proteomics. 2005 Jan;5(1):76-80. doi: 10.1002/pmic.200400862.
Data mining, finding and integration of information about proteins of interest, is an essential component in modern biological and biomedical research. Even when focusing on a single organism and only on a small number of proteins, there are often dozens fo data sources containing relevant information. We are developing PRIME, a protein information environment, to serve as a virtual central database which integrates distributed heterogeneous information about proteins (linked by common identifier). PRIME has powerful capabilities to visualize all kinds of protein annotation in specialized views. These views can be displayed side by side at the same time and can be synchronized in order to show simultaneously different aspects of identical proteins. These features allow a quick and comprehensive overview of properties of single proteins or protein sets.
数据挖掘，即寻找和整合感兴趣蛋白质的信息，是现代生物学和生物医学研究的重要组成部分。即使只关注单一生物体且仅关注少数蛋白质，通常也有数十个包含相关信息的数据源。我们正在开发PRIME，一种蛋白质信息环境，作为一个虚拟的中央数据库，整合关于蛋白质的分布式异构信息（通过通用标识符链接）。PRIME具有强大的功能，可在专门的视图中可视化各种蛋白质注释。这些视图可以同时并排显示，并且可以同步，以便同时展示同一蛋白质的不同方面。这些功能可快速全面地概述单个蛋白质或蛋白质集的特性。
