人类GSPT1基因（酵母GST1基因的人类同源基因）定位于染色体带16p13.1。
Mapping of the human GSPT1 gene, a human homolog of the yeast GST1 gene, to chromosomal band 16p13.1.
作者信息
Ozawa K, Murakami Y, Eki T, Yokoyama K, Soeda E, Hoshino S, Ui M, Hanaoka F
机构信息
Gene Bank, Riken Institute, Ibaraki, Japan.
出版信息
Somat Cell Mol Genet. 1992 Mar;18(2):189-94. doi: 10.1007/BF01233164.
The GSPT1 gene, a human homolog of the yeast GST1 gene (formerly named GST1-Hs), was mapped on human chromosome 16p13.1 by a combination of nonradioactive in situ hybridization and Giemsa staining. Southern blot hybridization with a panel of human-rodent somatic cells confirmed the location of the GSPT1 gene on chromosome 16 and also showed the existence of a homologous gene on the X chromosome. A breakpoint for nonrandom chromosome rearrangements has been found in the region of GSPT1 in patients with acute nonlymphocytic leukemia.
GSPT1基因是酵母GST1基因（原名为GST1-Hs）的人类同源基因，通过非放射性原位杂交和吉姆萨染色相结合的方法，将其定位在人类染色体16p13.1上。用人-啮齿动物体细胞系进行Southern印迹杂交，证实了GSPT1基因在16号染色体上的位置，同时也显示在X染色体上存在一个同源基因。在急性非淋巴细胞白血病患者中，已发现在GSPT1区域存在非随机染色体重排的断点。
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