Ohkawa Makio, Nishikawa Koichi, Takazawa Tomonori, Hinohara Hiroshi, Kunimoto Fumio, Goto Fumio
Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
Masui. 2005 Feb;54(2):172-6.
Fulminant myocarditis is a fetal disease characterized by a distinct viral prodrome, sudden onset of severe hemodynamic compromise, and marked myocardial inflammation. One possible therapy to improve the poor prognosis of such patients may be the implantation of circulatory support systems that allow myocardial recovery. We report here successful management of a patient with fulminant myocarditis using percutaneous cardiopulmonary support (PCPS), intra-aortic balloon pump (IABP), and continuous hemodiafiltration (CHDF). A 37-year-old Japanese man suddenly experienced cardiopulmonary dysfunction shortly after general fatigue, and was diagnosed as having fulminant myocarditis. PCPS was immediately initiated because catecholamine infusion and IABP were not enough to support circulation. Although severe dyskinesis was observed on his admission, cardiac function recovered twelve days after PCPS initiation with ejection fraction from 16% to 73%. Renal and hepatic failure also recovered with the improvement of cardiac function. We describe our clinical experiences in cardiogenic shock after acute fulminant myocarditis and discuss therapeutic guidelines for the use of PCPS, with its management and complications.
暴发性心肌炎是一种致命性疾病,其特征为有明显的病毒前驱症状、突然出现严重的血流动力学障碍以及显著的心肌炎症。改善此类患者不良预后的一种可能疗法或许是植入循环支持系统以使心肌恢复。我们在此报告一例使用经皮心肺支持(PCPS)、主动脉内球囊反搏(IABP)及连续性血液透析滤过(CHDF)成功治疗暴发性心肌炎患者的病例。一名37岁日本男性在全身疲劳后不久突然出现心肺功能障碍,被诊断为暴发性心肌炎。由于儿茶酚胺输注及IABP不足以支持循环,遂立即启动PCPS。尽管入院时观察到严重的心肌运动障碍,但在启动PCPS 12天后心脏功能恢复,射血分数从16%升至73%。随着心脏功能的改善,肾衰和肝衰也得以恢复。我们描述了急性暴发性心肌炎后心源性休克的临床经验,并讨论了使用PCPS的治疗指南及其管理和并发症。