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骨关节炎的治疗选择。

Treatment options for osteoarthritis.

作者信息

Snibbe Jason C, Gambardella Ralph A

机构信息

Beverly Hills Orthopedic Group, Beverly Hills, Calif, USA.

出版信息

Orthopedics. 2005 Feb;28(2 Suppl):s215-20. doi: 10.3928/0147-7447-20050202-06.

DOI:10.3928/0147-7447-20050202-06
PMID:15747609
Abstract

Osteoarthritis is the most common form of arthritis and can be a major source of disability. Many older patients continue to be active in sports-related activities. Therefore, treating an active patient with osteoarthritis is becoming more common. Physical therapy and weight loss continue to play a central role in the treatment of patients with osteoarthritis. Nonsteroidal anti-inflammatory drugs decrease inflammation and swelling, which makes physical therapy more effective. Intra-articular corticosteroids have been used for the treatment of osteoarthritis. However, no guidelines exist for the administration of corticosteroids and they can be associated with increased risk of tendon rupture and infection. Viscosupplementation has gained popularity in the treatment of osteoarthritis of the knee. Intra-articular injections of hyaluronic acid have been shown to decrease pain and improve functional outcomes.

摘要

骨关节炎是最常见的关节炎形式,可能是导致残疾的主要原因。许多老年患者仍积极参与与运动相关的活动。因此,治疗活跃的骨关节炎患者变得越来越普遍。物理治疗和减肥在骨关节炎患者的治疗中继续发挥核心作用。非甾体抗炎药可减轻炎症和肿胀,从而使物理治疗更有效。关节内注射皮质类固醇已用于治疗骨关节炎。然而,目前尚无皮质类固醇给药的指南,且它们可能与肌腱断裂和感染风险增加有关。粘弹性补充疗法在膝关节骨关节炎的治疗中越来越受欢迎。关节内注射透明质酸已被证明可减轻疼痛并改善功能结局。

相似文献

1
Treatment options for osteoarthritis.骨关节炎的治疗选择。
Orthopedics. 2005 Feb;28(2 Suppl):s215-20. doi: 10.3928/0147-7447-20050202-06.
2
Use of injections for osteoarthritis in joints and sports activity.注射疗法在关节骨关节炎及体育活动中的应用。
Clin Sports Med. 2005 Jan;24(1):83-91. doi: 10.1016/j.csm.2004.08.001.
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Corticosteroid compared with hyaluronic acid injections for the treatment of osteoarthritis of the knee.皮质类固醇与透明质酸注射治疗膝关节骨关节炎的比较。
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Osteoarthritis case study.骨关节炎病例研究。
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Is Local Viscosupplementation Injection Clinically Superior to Other Therapies in the Treatment of Osteoarthritis of the Knee: A Systematic Review of Overlapping Meta-analyses.局部粘弹性补充注射在治疗膝关节骨关节炎方面在临床上是否优于其他疗法:重叠荟萃分析的系统评价
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Intra-articular injections for osteoarthritis of the knee.膝关节骨关节炎的关节内注射治疗
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Editorial Commentary: Knee Hyaluronic Acid Viscosupplementation Reduces Osteoarthritis Pain.编者按:膝关节透明质酸粘弹性补充疗法可减轻骨关节炎疼痛。
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Intra-articular therapy in osteoarthritis.骨关节炎的关节内治疗
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[Conservative therapy of osteoarthritis].[骨关节炎的保守治疗]
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引用本文的文献

1
Corticosteroid transdermal delivery significantly improves arthritis pain and functional disability.皮质类固醇经皮给药可显著改善关节炎疼痛和功能障碍。
Drug Deliv Transl Res. 2017 Feb;7(1):156-161. doi: 10.1007/s13346-016-0340-9.
2
Clinical efficacy of intra-articular injections in knee osteoarthritis: a prospective randomized study comparing hyaluronic acid and betamethasone.关节腔内注射治疗膝关节骨关节炎的临床疗效:一项比较透明质酸和倍他米松的前瞻性随机研究。
Open Access Rheumatol. 2015 Jan 9;7:9-18. doi: 10.2147/OARRR.S74553. eCollection 2015.
3
Hyaluronic acid compared with corticosteroid injections for the treatment of osteoarthritis of the knee: a randomized control trail.
透明质酸与皮质类固醇注射治疗膝骨关节炎的比较:一项随机对照试验。
Springerplus. 2016 Apr 12;5:442. doi: 10.1186/s40064-016-2020-0. eCollection 2016.
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Corticosteroid and Anesthetic Injections for Muscle Strains and Ligament Sprains in the NFL.NFL 中肌肉拉伤和韧带扭伤的皮质类固醇和麻醉注射。
HSS J. 2014 Jul;10(2):136-42. doi: 10.1007/s11420-014-9395-7. Epub 2014 May 21.
5
Strategies for managing osteoarthritis.骨关节炎的管理策略。
Int J Behav Med. 2012 Sep;19(3):298-307. doi: 10.1007/s12529-011-9168-3.
6
New methods to diagnose and treat cartilage degeneration.新方法诊断和治疗软骨退化。
Nat Rev Rheumatol. 2009 Nov;5(11):599-607. doi: 10.1038/nrrheum.2009.204. Epub 2009 Sep 29.
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Glucocorticosteroids in football: use and misuse.足球运动中的糖皮质激素:使用与滥用
Br J Sports Med. 2006 Jul;40 Suppl 1(Suppl 1):i48-54. doi: 10.1136/bjsm.2006.027599.