Molls M
Institut und Poliklinik für Strahlentherapie und Radiologische Onkologie, Technische Universität, München.
Strahlenther Onkol. 1992 Apr;168(4):183-90.
After a short introduction the first part of the editorial describes biological and technical fundamentals of clinical hyperthermia. Results obtained in the field of thermobiology lead to conclusions for the clinical application of hyperthermia in combination with radiation therapy. These are concerned with the direct cytotoxic effect of heat, protection of normal tissues, impact of blood flow on the quality of a hyperthermic treatment, thermotolerance, the necessary number of heat treatments, and the radiosensitizing effect of heat. The technical paragraph outlines localized heating techniques, thermometry methods and important aspects of quality assurance, thermal dosimetry and treatment planning.
在简短的引言之后，社论的第一部分描述了临床热疗的生物学和技术基础。热生物学领域所取得的成果为热疗与放射治疗联合应用于临床提供了结论依据。这些结论涉及热的直接细胞毒性作用、正常组织的保护、血流对热疗质量的影响、热耐受性、热疗所需的次数以及热的放射增敏作用。技术部分概述了局部加热技术、温度测量方法以及质量保证、热剂量学和治疗计划的重要方面。
