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表皮生长因子受体2073基因多态性的纯合子和等位基因与子宫内膜异位症和平滑肌瘤的易感性增加有关。

T homozygote and allele of epidermal growth factor receptor 2073 gene polymorphism are associated with higher susceptibility to endometriosis and leiomyomas.

作者信息

Hsieh Yao-Yuan, Chang Chi-Chen, Tsai Fuu-Jen, Lin Cheng-Chieh, Tsai Chang-Hai

机构信息

Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan.

出版信息

Fertil Steril. 2005 Mar;83(3):796-9. doi: 10.1016/j.fertnstert.2004.08.032.

DOI:10.1016/j.fertnstert.2004.08.032
PMID:15749523
Abstract

Epidermal growth factor receptor (EGFR) is a regulator of angiogenesis and mediator of sex steroid-induced cell growth and differentiation. We observed that EGFR gene 2073*T-related genotypes and allele are associated with higher susceptibilities to endometriosis and leiomyoma.

摘要

表皮生长因子受体（EGFR）是血管生成的调节因子，也是性类固醇诱导的细胞生长和分化的介质。我们观察到，EGFR基因2073*T相关的基因型和等位基因与子宫内膜异位症和平滑肌瘤的易感性增加有关。

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1
T homozygote and allele of epidermal growth factor receptor 2073 gene polymorphism are associated with higher susceptibility to endometriosis and leiomyomas.表皮生长因子受体2073基因多态性的纯合子和等位基因与子宫内膜异位症和平滑肌瘤的易感性增加有关。
Fertil Steril. 2005 Mar;83(3):796-9. doi: 10.1016/j.fertnstert.2004.08.032.
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Estrogen receptor alpha-351 XbaI*G and -397 PvuII*C-related genotypes and alleles are associated with higher susceptibilities of endometriosis and leiomyoma.雌激素受体α-351 XbaI*G和-397 PvuII*C相关的基因型及等位基因与子宫内膜异位症和平滑肌瘤的较高易感性相关。
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T allele for VEGF gene-460 polymorphism at the 5'-untranslated region: association with a higher susceptibility to endometriosis.血管内皮生长因子（VEGF）基因5'-非翻译区-460多态性的T等位基因：与子宫内膜异位症的易感性增加相关。
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