Kern Rolf, Perren Fabienne, Kreisel Stefan, Szabo Kristina, Hennerici Michael, Meairs Stephen
Department of Neurology, Universitätsklinikum Mannheim, University of Heidelberg, Mannheim, Germany.
Ultrasound Med Biol. 2005 Mar;31(3):311-5. doi: 10.1016/j.ultrasmedbio.2004.12.006.
The purpose of this study was to define a standardized multiplanar approach for transcranial ultrasound (US) imaging of brain parenchyma based on matched data from 3-D US and 3-D magnetic resonance imaging (MRI). The potential and limitations of multiple insonation planes in transverse and coronal orientation were evaluated for the visualization of intracranial landmarks in 60 healthy individuals (18 to 83 years old, mean 41.4 years) with sufficient temporal bone windows. Landmarks regularly visualized even in moderate sonographic conditions with identification rates of >75% were mesencephalon, pons, third ventricle, lateral ventricles, falx, thalamus, basal ganglia, pineal gland and temporal lobe. Identification of medulla oblongata, fourth ventricle, cerebellar structures, hippocampus, insula, frontal, parietal and occipital lobes was more difficult (<75%). We hypothesize that multiplanar transcranial US images, with standardized specification of tilt angles and orientation, not only allow comparison with other neuroimaging modalities, but may also provide a more objective framework for US monitoring of cerebral disease than freehand scanning.
本研究的目的是基于三维超声（US）和三维磁共振成像（MRI）的匹配数据，定义一种用于脑实质经颅超声（US）成像的标准化多平面方法。对60名颞骨窗良好的健康个体（年龄18至83岁，平均41.4岁）进行评估，以确定横向和冠状方向上多个声束平面在可视化颅内标志物方面的潜力和局限性。即使在中等超声条件下，识别率>75%的常规可视化标志物有中脑、脑桥、第三脑室、侧脑室、大脑镰、丘脑、基底神经节、松果体和颞叶。延髓、第四脑室、小脑结构、海马体、岛叶、额叶、顶叶和枕叶的识别较困难（<75%）。我们推测，具有标准化倾斜角度和方向规格的多平面经颅US图像，不仅可以与其他神经成像方式进行比较，而且与徒手扫描相比，还可能为US监测脑部疾病提供一个更客观的框架。
