Balédent Olivier, Fin Loïc, Khuoy Louis, Ambarki Khalid, Gauvin Anne-Cécile, Gondry-Jouet Catherine, Meyer Marc-Etienne
Department of Imaging and Biophysics, University Hospital, Jules Verne University of Picardie, Amiens, France.
J Magn Reson Imaging. 2006 Nov;24(5):995-1004. doi: 10.1002/jmri.20722.
To evaluate the contributions of phase-contrast magnetic resonance (PCMR) and transcranial color Doppler (TCCD) imaging in the investigation of cerebral hydrodynamics.
A total of 13 healthy subjects were studied. Blood velocity measurements were performed with TCCD and gated PCMR imaging in major intracranial and extracranial arteries stages. Peak systolic velocity and end-diastolic velocity were extracted to establish correlations between TCCD and PCMR imaging. Cerebral blood flow (CBF) and intracranial volume change (IVC) during the cardiac cycle were calculated, taking into account cerebrospinal fluid (CSF) oscillations.
Despite an underestimation of velocities with PCMR imaging, significant correlations were observed for velocity measurements between the two modalities in extracranial vessels, but were poorly correlated in intracranial vessels. PCMR data processing gave a mean CBF of 690+/-90 mL/minute.
PCMR imaging provides complementary information to TCCD to assess various intracranial parameters such as instantaneous velocities, blood and CSF flow distributions, volume variation, or pressure regulation mechanisms during cardiac cycles.
评估相位对比磁共振成像（PCMR）和经颅彩色多普勒（TCCD）成像在脑血流动力学研究中的作用。
共研究了13名健康受试者。在主要颅内和颅外动脉阶段，使用TCCD和门控PCMR成像进行血流速度测量。提取收缩期峰值速度和舒张末期速度，以建立TCCD与PCMR成像之间的相关性。考虑脑脊液（CSF）振荡，计算心动周期中的脑血流量（CBF）和颅内体积变化（IVC）。
尽管PCMR成像对速度有低估，但两种方法在颅外血管的速度测量中观察到显著相关性，而在颅内血管中相关性较差。PCMR数据处理得出平均CBF为690±90毫升/分钟。
PCMR成像为TCCD提供补充信息，以评估各种颅内参数，如瞬时速度、血液和脑脊液流动分布、体积变化或心动周期中的压力调节机制。
