一位失语女性：甲氨蝶呤神经毒性报告
A woman who couldn't speak: report of methotrexate neurotoxicity.
作者信息
Szawarski P, Chapman C S
机构信息
Glenfield General Hospital, Leicester, UK.
出版信息
Postgrad Med J. 2005 Mar;81(953):194-5. doi: 10.1136/pgmj.2003.018267.
Abstract
The association between methotrexate therapy and idiosyncratic neurological complications is well recognised in children. This case illustrates the importance of considering the diagnosis of methotrexate toxicity in an adult patient with behavioural and speech disturbances, who received it by intrathecal route only and in whom the only indicator was an abnormal electroencephalographic study.
摘要
甲氨蝶呤治疗与儿童特发性神经并发症之间的关联已得到充分认识。本病例说明了对于一名仅通过鞘内途径接受甲氨蝶呤治疗、出现行为和言语障碍且唯一指标为脑电图检查异常的成年患者，考虑甲氨蝶呤毒性诊断的重要性。
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