口服L-精氨酸治疗囊性纤维化的一项初步研究。

A pilot study of oral L-arginine in cystic fibrosis.

作者信息

Everard M L, Donnelly D

出版信息

J Cyst Fibros. 2005 Mar;4(1):67-9. doi: 10.1016/j.jcf.2004.10.001.

DOI:10.1016/j.jcf.2004.10.001

Abstract

Exhaled nitric oxide has previously been found to be low in cystic fibrosis. The aim of this study was to determine whether exhaled nitric oxide levels would increase in response to oral L-arginine supplementation administered daily for 4 weeks. Exhaled and nasal nitric oxide was measured weekly. Plasma L-arginine levels increased in response to supplementation but this was not reflected in an increase in eNO levels.

摘要

先前已发现呼出一氧化氮在囊性纤维化患者中水平较低。本研究的目的是确定每日口服补充L-精氨酸4周后呼出一氧化氮水平是否会升高。每周测量呼出和鼻腔一氧化氮水平。补充后血浆L-精氨酸水平升高，但这并未反映在呼出一氧化氮水平的增加上。