Cross J H, Harrison C J, Preston P R, Rushton D I, Newell S J, Morgan M E, Durbin G M
Birmingham Maternity Hospital, Queen Elizabeth Medical Centre.
Arch Dis Child. 1992 Mar;67(3):307-11. doi: 10.1136/adc.67.3.307.
A previously unrecognised and distinctive pattern of severe brain injury in extreme preterm neonates was observed recently. Fifteen neonates of birth weight 600-1270 g and gestation of 24-32 weeks showed relatively late development on cerebral ultrasound scan of extensive dense and cystic lesions involving the periphery of the brain. The extent of the changes was confirmed at postmortem examination in 11 babies. These changes have been called encephaloclastic porencephaly. The population of babies in whom this has occurred and their clinical outcome has been reviewed, with comparison between the evolution of the ultrasound changes and pathological findings at postmortem examination.
最近观察到极早产儿中一种以前未被认识且独特的严重脑损伤模式。15例出生体重600 - 1270克、孕周24 - 32周的新生儿在脑超声扫描中显示出相对较晚出现的广泛致密和囊性病变，累及脑周边区域。11例婴儿在死后检查中证实了这些变化的程度。这些变化被称为脑破坏性孔洞脑畸形。对发生这种情况的婴儿群体及其临床结局进行了回顾，并比较了超声变化的演变与死后检查的病理结果。
