活性环氧化合物和氮杂环丙烷与芳基硼酸酯的温和无金属顺式立体选择性开环反应。
Mild metal-free syn-stereoselective ring opening of activated epoxides and aziridines with aryl borates.
作者信息
Pineschi Mauro, Bertolini Ferruccio, Haak Robert M, Crotti Paolo, Macchia Franco
机构信息
Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126, Pisa, Italy.
出版信息
Chem Commun (Camb). 2005 Mar 21(11):1426-8. doi: 10.1039/b416517a. Epub 2005 Jan 21.
DOI:10.1039/b416517a
PMID:15756325
Abstract
A conceptually new, simple and practical method for the syn-nucleophilic displacement of aryl and vinyl epoxides and aryl aziridines with (substituted) phenols, using aryl borates as activating nucleophiles under neutral conditions, is reported.
摘要
报道了一种概念上新的、简单且实用的方法，即在中性条件下，使用芳基硼酸酯作为活化亲核试剂，使芳基和乙烯基环氧化物以及芳基氮丙啶与（取代）酚发生亲核取代反应。
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