颅内脑膜疾病：对比增强磁共振成像与液体衰减反转恢复序列及脂肪抑制T1加权序列的比较
Intracranial meningeal disease: comparison of contrast-enhanced MR imaging with fluid-attenuated inversion recovery and fat-suppressed T1-weighted sequences.
作者信息
Galassi Waneerat, Phuttharak Warinthorn, Hesselink John R, Healy John F, Dietrich Rosalind B, Imbesi Steven G
机构信息
Department of Radiology, University of California, San Diego, Medical Center, San Diego, California 92103-8756, USA.
出版信息
AJNR Am J Neuroradiol. 2005 Mar;26(3):553-9.
BACKGROUND AND PURPOSE
Contrast-enhanced fluid-attenuated inversion recovery (FLAIR) imaging has been reported to have higher sensitivity for detecting leptomeningeal disease compared with contrast-enhanced T1-weighted MR imaging. The purpose of this study was to compare contrast-enhanced T1-weighted MR images with fat suppression to contrast-enhanced FLAIR images to determine which sequence was superior for depicting meningeal disease.
METHODS
We reviewed MR images of 24 patients (35 studies) with a variety of meningeal diseases. The MR imaging protocol included contrast-enhanced T1-weighted MR images with fat suppression (FS) and contrast-enhanced fluid-attenuated inversion recovery (FLAIR) images that were reviewed by three neuroradiologists and were assigned a rating of positive, equivocal, or negative for abnormal meningeal enhancement. The two sequences were compared side by side to determine which better depicted meningeal disease.
RESULTS
Abnormal meningeal enhancement was positive in 35 contrast-enhanced T1-weighted MR images with FS and in 33 contrast-enhanced FLAIR studies. In the first group, which had the T1-weighted sequence acquired first (21 of 33 studies), contrast-enhanced T1-weighted images with FS showed superior contrast enhancement in 11 studies (52%), inferior contrast enhancement in six studies (29%), and equal contrast enhancement in four studies (19%) compared with the contrast-enhanced FLAIR images. In the second group, which had the FLAIR sequence acquired first (12 of 33), contrast-enhanced T1-weighted images with FS showed superior contrast enhancement in seven studies (58%), inferior contrast enhancement in two studies (17%), and equal contrast enhancement in three studies (25%).
CONCLUSION
Contrast-enhanced T1-weighted MR imaging with FS is superior to contrast-enhanced FLAIR imaging in most cases for depicting intracranial meningeal diseases.
背景与目的
与对比增强T1加权磁共振成像相比，对比增强液体衰减反转恢复（FLAIR）成像在检测软脑膜疾病方面具有更高的敏感性。本研究的目的是比较脂肪抑制的对比增强T1加权磁共振图像与对比增强FLAIR图像，以确定哪种序列在描绘脑膜疾病方面更具优势。
方法
我们回顾了24例患有各种脑膜疾病患者的磁共振图像（共35项研究）。磁共振成像方案包括脂肪抑制的对比增强T1加权磁共振图像和对比增强液体衰减反转恢复（FLAIR）图像，由三位神经放射科医生进行评估，并对脑膜异常强化给予阳性、可疑或阴性评级。将这两种序列并排比较，以确定哪种序列能更好地描绘脑膜疾病。
结果
在35项脂肪抑制的对比增强T1加权磁共振图像和33项对比增强FLAIR研究中，脑膜异常强化均为阳性。在第一组中，先采集T1加权序列（33项研究中的21项），与对比增强FLAIR图像相比，脂肪抑制的对比增强T1加权图像在11项研究中显示出更好的对比增强效果（52%），在6项研究中显示出较差的对比增强效果（29%），在4项研究中显示出相同的对比增强效果（19%）。在第二组中，先采集FLAIR序列（33项研究中的12项），脂肪抑制的对比增强T1加权图像在7项研究中显示出更好的对比增强效果（58%），在2项研究中显示出较差的对比增强效果（17%），在3项研究中显示出相同的对比增强效果（25%）。
结论
在大多数情况下，脂肪抑制的对比增强T1加权磁共振成像在描绘颅内脑膜疾病方面优于对比增强FLAIR成像。
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