Brunette Mary F, Mueser Kim T, Drake Robert E
New Hampshire--Dartmouth Psychiatric Research Center and Dartmouth Medical School NH, USA.
Drug Alcohol Rev. 2004 Dec;23(4):471-81. doi: 10.1080/09595230412331324590.
Substance use disorder is the most common and clinically significant co-morbidity among clients with severe mental illnesses, associated with poor treatment response, homelessness and other adverse outcomes. Residential programs for clients with dual disorders integrate mental health treatment, substance abuse interventions, housing and other supports. Ten controlled studies suggest that greater levels of integration of substance abuse and mental health services are more effective than less integration. Because the research is limited by methodological problems, further research is needed to establish the effectiveness of residential programs, to characterize important program elements, to establish methods to improve engagement into and retention in residential programs and to clarify which clients benefit from this type of service.
物质使用障碍是重度精神疾病患者中最常见且具有临床意义的共病，与治疗反应不佳、无家可归及其他不良后果相关。针对双重障碍患者的住院项目整合了心理健康治疗、药物滥用干预、住房及其他支持措施。十项对照研究表明，药物滥用和心理健康服务的整合程度越高，效果越好。由于该研究受到方法学问题的限制，需要进一步研究以确定住院项目的有效性，明确重要的项目要素，确定提高参与住院项目及维持项目参与度的方法，并阐明哪些患者能从此类服务中获益。
