Abejón D, García del Valle S, Nieto C, Delgado C, Gómez-Arnau J I
Area de Anestesia, Reanimación y Cuidados Críticos, Unidad de Dolor, Fundación Hospital Alcorcón, Alcorcón, Madrid.
Rev Esp Anestesiol Reanim. 2005 Feb;52(2):109-14.
To describe the use of pulsed radiofrequency (PRF) to treat 2 cases of glossopharyngeal neuralgia, 1 idiopathic and 1 secondary.
The first case involved a man diagnosed with Hodgkin's lymphoma involving the tonsils and manifesting as glossopharyngeal neuralgia that was refractory to all treatment approaches tried, including opioids and neuromodulation. The second case involved a patient diagnosed with essential glossopharyngeal neuralgia that was also resistant to drug treatment. The PRF procedure was performed in the operating room on an outpatient basis, under fluoroscopic guidance and with conventional monitoring. No perioperative events were reported.
The treatment was effective for both patients, leading to decreases in visual analog scale pain reports between 5 and 7 points that were maintained over 6 months, although improvement for the patient with essential neuralgia was less intense and of shorter duration. Overall self-reported improvement assessed subjectively 6 months after PRF was 75% for the patient with Hodgkin's lymphoma and 50% for the patient with essential neuralgia, for whom a second PRF procedure was scheduled. Neither patient suffered complications or side effects that were potentially attributable to the procedure.
PRF seems to be a safe, effective approach to treating neuralgia of the glossopharyngeal nerve, whether the condition is essential or secondary to another process. It is possible that if the condition is secondary, the clinical response may be greater in intensity and last longer.
描述使用脉冲射频（PRF）治疗2例舌咽神经痛患者的情况，其中1例为特发性，1例为继发性。
首例患者为一名男性，被诊断为霍奇金淋巴瘤累及扁桃体，并表现为舌咽神经痛，对包括阿片类药物和神经调节在内的所有尝试的治疗方法均无效。第二例患者被诊断为原发性舌咽神经痛，对药物治疗也有抵抗。PRF手术在门诊手术室进行，在荧光镜引导下并采用常规监测。未报告围手术期事件。
该治疗对两名患者均有效，导致视觉模拟量表疼痛评分下降5至7分，并在6个月内保持，尽管原发性神经痛患者的改善程度较小且持续时间较短。PRF术后6个月主观评估的总体自我报告改善情况，霍奇金淋巴瘤患者为75%，原发性神经痛患者为50%，后者计划进行第二次PRF手术。两名患者均未出现可能归因于该手术的并发症或副作用。
PRF似乎是治疗舌咽神经痛的一种安全、有效的方法，无论该疾病是原发性还是继发于其他疾病。如果是继发性疾病，临床反应可能强度更大且持续时间更长。
