Grant Jon E, Menard William, Pagano Maria E, Fay Christina, Phillips Katharine A
Butler Hospital and the Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02906, USA.
J Clin Psychiatry. 2005 Mar;66(3):309-16; quiz 404-5. doi: 10.4088/jcp.v66n0306.
Little is known about substance use disorders (SUDs) in individuals with body dysmorphic disorder (BDD). Although studies have examined SUD comorbidity in BDD, no previous studies have examined clinical correlates of SUD comorbidity.
We examined rates and clinical correlates of comorbid SUDs in 176 consecutive subjects with DSM-IV BDD (71% female; mean +/- SD age = 32.5 +/- 12.3 years). Comorbidity data were obtained with the Structured Clinical Interview for DSM-IV. BDD severity was assessed with the Yale-Brown Obsessive Compulsive Scale Modified for BDD, and delusionality (insight) was assessed with the Brown Assessment of Beliefs Scale. Quality of life and social/occupational functioning were examined using the Social Adjustment Scale, Quality of Life Enjoyment and Satisfaction Questionnaire, Medical Outcomes Study 36-Item Short-Form Health Survey, and Range of Impaired Functioning Tool. All variables were compared in BDD subjects with and without lifetime and current SUDs. Data were collected from January 2001 to June 2003.
48.9% of BDD subjects (N = 86) had a lifetime SUD, 29.5% had lifetime substance abuse, and 35.8% had lifetime substance dependence (most commonly, alcohol dependence [29.0%]). 17% (N = 30) had current substance abuse or dependence (9.1% reported current substance abuse, and 9.7% reported current dependence). 68% of subjects with a lifetime SUD reported that BDD contributed to their SUD. There were far more similarities than differences between subjects with a comorbid SUD and those without an SUD, although those with a lifetime SUD had a significantly higher rate of suicide attempts (p = .004).
These preliminary results suggest that SUDs are very common in individuals with BDD. Subjects with and without a comorbid SUD were similar in most domains that were examined.
关于身体变形障碍(BDD)患者的物质使用障碍(SUDs),人们知之甚少。尽管已有研究探讨了BDD中的SUD共病情况,但此前尚无研究考察SUD共病的临床相关因素。
我们对176例符合《精神疾病诊断与统计手册》第四版(DSM-IV)标准的BDD连续患者(71%为女性;平均年龄±标准差 = 32.5±12.3岁)的SUD共病发生率及临床相关因素进行了研究。共病数据通过DSM-IV的结构化临床访谈获取。BDD严重程度采用针对BDD修改后的耶鲁-布朗强迫量表进行评估,妄想(自知力)采用布朗信念评估量表进行评估。使用社会适应量表、生活质量享受与满意度问卷、医学结果研究36项简式健康调查以及功能受损范围工具对生活质量和社会/职业功能进行了考察。对有和无终生及当前SUD的BDD患者的所有变量进行了比较。数据收集时间为2001年1月至2003年6月。
48.9%的BDD患者(N = 86)有终生SUD,29.5%有终生物质滥用,35.8%有终生物质依赖(最常见的是酒精依赖[29.0%])。17%(N = 30)有当前物质滥用或依赖(9.1%报告当前物质滥用,9.7%报告当前依赖)。68%有终生SUD的患者报告BDD导致了他们的SUD。有SUD共病的患者与无SUD的患者之间的相似之处远多于差异,尽管有终生SUD的患者自杀未遂率显著更高(p = .004)。
这些初步结果表明,SUD在BDD患者中非常常见。有和无SUD共病的患者在大多数考察领域中相似。