晚期先天性梅毒直至成年才得到治疗而引发的眼球痨。
Phthisis bulbi caused by late congenital syphilis untreated until adulthood.
作者信息
Uchiyama Kayo, Tsuchihara Katsuma, Horimoto Takashi, Karasawa Tadahiro, Sugiyama Kazuhisa
机构信息
Department of Ophthalmology, Kanazawa Red Cross Hospital, Ishikawa, Japan.
出版信息
Am J Ophthalmol. 2005 Mar;139(3):545-7. doi: 10.1016/j.ajo.2004.08.056.
PURPOSE
To report a case of phthisis bulbi resulting from late congenital syphilis untreated until adulthood.
DESIGN
Observational case report.
METHODS
We report clinical and laboratory evaluations of a 43-year-old woman who presented with a palpebral ulcer of the right eye.
RESULTS
The patient had a gummatous palpebral ulcer and a phthisis bulbi in the right eye and a gumma on the left eyelid. A silent interstitial keratitis of the left eye was detected. The patient had hearing loss in the right ear, her nose was missing, and her right leg had been amputated. Treponemal pallidum hemagglutination (TPHA) test was positive. Although we administered intensive oral penicillin, the clinical symptoms of the patient did not improve.
CONCLUSIONS
This is a rare case of phthisis bulbi resulting from late congenital syphilis. We emphasize that treatment for late congenital syphilis must be carried out early and completely.
目的
报告一例因晚期先天性梅毒直至成年才接受治疗而导致眼球痨的病例。
设计
观察性病例报告。
方法
我们报告了一名43岁女性的临床和实验室评估情况，该患者右眼出现睑部溃疡。
结果
患者右眼有梅毒瘤性睑部溃疡和眼球痨，左眼眼睑有梅毒瘤。检测发现左眼存在无症状性间质性角膜炎。患者右耳听力丧失，鼻子缺失，右腿已截肢。梅毒螺旋体血凝试验（TPHA）呈阳性。尽管我们给予了强化口服青霉素治疗，但患者的临床症状并未改善。
结论
这是一例由晚期先天性梅毒导致眼球痨的罕见病例。我们强调，晚期先天性梅毒的治疗必须尽早且彻底地进行。
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