Xanthoma disseminatum with bilateral epibulbar involvement.

PURPOSE

To describe the ocular involvement in xanthoma disseminatum.

DESIGN

Case report and literature review.

METHODS

Histopathologic study of excised conjunctival tumor and clinical follow-up.

RESULTS

A 29-year-old woman with normal serum lipoproteins developed widespread xanthomas of the skin, throat, and episclera. There were no signs of recurrence 12 months after removal of the conjunctival xanthomas.

CONCLUSIONS

Xanthoma disseminatum is a rare condition for which there is no medical treatment. The distinction between the normolipemic xanthomatoses awaits a better understanding of their pathogenesis. Surgical removal of episcleral xanthomas can be successful, but long-term follow-up of such patients has been limited.