双侧球结膜黄色瘤——一例报告。
Bilateral epibulbar xanthomas--a case report.
机构信息
Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
出版信息
Cornea. 2010 Feb;29(2):225-7. doi: 10.1097/ICO.0b013e3181a3c419.
PURPOSE
To report bilateral epibulbar xanthomatous lesions in an adult with a normal serum lipid profile and no cutaneous or systemic features of a histiocytic disease.
METHODS
Clinicopathologic report.
RESULTS
A 44-year-old man presented with gradually enlarging yellow epibulbar masses in both eyes. The lesions had recurred after excisions performed 2 years previously. Systemic evaluation was normal. Excisional biopsies were performed, and histological examination revealed numerous foamy histiocytes with scattered Touton giant cells and lymphocytes. No recurrence was observed after 1 year of follow-up.
CONCLUSION
Xanthomatous epibulbar lesions are exceedingly rare and may occur as an isolated finding. Evaluation should be directed toward detecting underlying non-Langerhans cell histiocytic diseases and disorders of lipid metabolism. Recurrent lesions may be successfully treated by surgical excision.
目的
报告一例血清脂质谱正常且无组织细胞疾病皮肤或全身特征的成人双侧球结膜黄色瘤病变。
方法
临床病理报告。
结果
一名 44 岁男性因双眼逐渐增大的黄色球结膜肿块就诊。2 年前行切除术，病变复发。全身评估正常。行切除活检，组织学检查显示大量泡沫状组织细胞，散在 Touton 巨细胞和淋巴细胞。随访 1 年后未见复发。
结论
黄色瘤性球结膜病变极为罕见，可能为孤立性表现。评估应针对潜在的非朗格汉斯细胞组织细胞疾病和脂质代谢紊乱。复发性病变可通过手术切除成功治疗。
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