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巴基斯坦城市全科医生对高血压的治疗方法:令人不安的实际趋势

General practitioners' approach to hypertension in urban Pakistan: disturbing trends in practice.

作者信息

Jafar Tazeen H, Jessani Saleem, Jafary Fahim H, Ishaq Mohammad, Orakzai Raza, Orakzai Sarwar, Levey Andrew S, Chaturvedi Nish

机构信息

Section of Nephrology, Department of Medicine, Aga Khan University, PO Box 3500, Stadium Road, Karachi, 74800, Pakistan.

出版信息

Circulation. 2005 Mar 15;111(10):1278-83. doi: 10.1161/01.CIR.0000157698.78949.D7.

Abstract

BACKGROUND

Control of blood pressure (BP) remains suboptimal worldwide. The objective of this study was to determine whether (primary) general practitioners' (GPs) approach to high BP is in accordance with international guidelines.

METHODS AND RESULTS

We conducted a cross-sectional survey of 1000 randomly selected GPs from urban areas in Pakistan during 2002. A rigorously developed questionnaire on (1) type of practice and (2) detection, (3) evaluation, (4) treatment, and (5) source of information about high BP was administered by trained medical personnel. A total of 1051 GPs were approached, and 1000 (95%) consented to enroll; 766 were male and 655 had been in practice > or =10 years. The average number of patients (SD) seen per day was 48.2 (42.7). Overall, 30.6% (29.0% to 32.3%) and 79.7% (78.3% to 81.0%) of GPs used incorrect BP cutoffs to diagnose hypertension in patients <60 and > or =60 years, respectively. Appropriate therapy for hypertension in the elderly was initiated by only 34.7% (33.0% to 36.3%) of GPs. The use of sedatives either alone (23.8%) or in combination with antihypertensive agents as first-line medication for lowering BP was reported by 45.0% (43.2% to 46.7%). Thiazide diuretics were rarely prescribed (4.2%). Sublingual antihypertensive agents were prescribed by 68.7% (67.1% to 70.3%) of GPs for treating very high levels of BP. The practices of recent graduates from medical school were not better than those of older graduates.

CONCLUSIONS

GPs in Pakistan underdiagnose and undertreat high BP, especially in the elderly. Our findings underscore the need for urgent revision of teaching curricula in medical schools with regard to the risks, complications, and management of hypertension, as well as the initiation of widespread and intensive continuing medical education for all physicians involved in the management of patients with hypertension. Particular efforts are needed to encourage the use of low-cost thiazide diuretics as antihypertensive agents in developing countries.

摘要

背景

全球范围内血压控制仍未达到最佳水平。本研究的目的是确定(初级)全科医生(GP)处理高血压的方法是否符合国际指南。

方法与结果

2002年期间,我们对从巴基斯坦城市地区随机选取的1000名全科医生进行了横断面调查。由经过培训的医务人员发放一份精心编制的问卷,内容涉及(1)执业类型以及(2)高血压的检测、(3)评估、(4)治疗和(5)信息来源。共接触了1051名全科医生,1000名(95%)同意参与;其中766名男性,655名执业≥10年。每天平均看诊患者数(标准差)为48.2(42.7)。总体而言,分别有30.6%(29.0%至32.3%)和79.7%(78.3%至81.0%)的全科医生在诊断<60岁和≥60岁患者的高血压时使用了不正确的血压临界值。仅有34.7%(33.0%至36.3%)的全科医生对老年高血压患者启动了适当治疗。45.0%(43.2%至46.7%)的医生报告单独使用镇静剂(23.8%)或与抗高血压药物联合作为降低血压的一线用药。噻嗪类利尿剂很少被处方(4.2%)。68.7%(67.1%至70.3%)的全科医生为治疗极高血压水平而开具舌下抗高血压药物。医学院校应届毕业生的做法并不优于年长毕业生。

结论

巴基斯坦的全科医生对高血压诊断不足且治疗不足,尤其是在老年人中。我们的研究结果强调,医学院校的教学课程迫切需要修订,内容涉及高血压的风险、并发症和管理,同时需要为所有参与高血压患者管理的医生开展广泛且深入的继续医学教育。在发展中国家,尤其需要努力鼓励使用低成本的噻嗪类利尿剂作为抗高血压药物。

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