Uchiyama Kiyoshi, Kaminaga Tatsuro, Waida Mitsuo, Yasuda Masami, Chikamatsu Takashi
Department of Radiology, Teikyo University Medical School, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
Ann Nucl Med. 2005 Feb;19(1):9-15. doi: 10.1007/BF02986329.
The effectiveness of the automated motion correction software (INSTILL, Philips Medical Systems Co. Ltd., Andover, USA) proposed by Matsumoto et al. to prevent motion artifact in quantitative gated SPECT, was tested with a technetium-99m point source and cardiac phantom. INSTILL well corrected the error due to point source movement during acquisition up to a distance of 5 pixels (32.8 mm) in the right and caudal directions, as well as with a distance of up to 7 pixels (45.9 mm) of oblique (caudal-right 45 degree) movement inside the coronal plane. End-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were also well adjusted with INSTILL, for up to 3 pixels (19.7 mm) movement of the dynamic cardiac phantom during acquisition in the right, caudal and oblique directions. The respective maximum error with one, two and three pixel movement was 9, 24 and 23 ml in EDV, and 8, 22 and 21 ml in ESV. The maximum error of EF was 3% in all conditions without INSTILL. After using INSTILL, the maximum residual errors of both EDV and ESV were 7 ml and that of EF was 3% in all conditions. Quantitative gated SPECT software with INSTILL will calculate EDV, ESV and EF against movement of patients in the coronal plane. INSTILL is therefore concluded to be a reliable software for motion correction in clinical use.
松本等人提出的用于预防定量门控单光子发射计算机断层扫描（SPECT）中运动伪影的自动运动校正软件（INSTILL，飞利浦医疗系统有限公司，美国安多弗），使用锝-99m点源和心脏模型进行了测试。INSTILL能够很好地校正采集期间点源在右向和尾向移动达5像素（32.8毫米）时产生的误差，以及在冠状面内斜向（尾向-右45度）移动达7像素（45.9毫米）时产生的误差。对于动态心脏模型在采集期间在右向、尾向和斜向移动达3像素（19.7毫米）的情况，舒张末期容积（EDV）、收缩末期容积（ESV）和射血分数（EF）也能通过INSTILL得到很好的调整。在EDV中，1像素、2像素和3像素移动时各自的最大误差分别为9毫升、24毫升和23毫升，在ESV中分别为8毫升、22毫升和21毫升。在所有未使用INSTILL的情况下，EF的最大误差为3%。使用INSTILL后，在所有情况下，EDV和ESV的最大残余误差均为7毫升，EF的最大残余误差为3%。带有INSTILL的定量门控SPECT软件将针对患者在冠状面内的移动计算EDV、ESV和EF。因此得出结论，INSTILL是临床使用中一种可靠的运动校正软件。
