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使用闪烁体-光电二极管相机通过门控单光子发射计算机断层扫描验证左心室功能:动态心肌模型研究

Validation of left ventricular function from gated single photon computed emission tomography by using a scintillator-photodiode camera: a dynamic myocardial phantom study.

作者信息

Kubo N, Mabuchi M, Katoh C, Arai H, Morita K, Tsukamoto E, Morita Y, Tamaki N

机构信息

Department of Radiological Technology, College of Medical Technology, Hokkaido University Hospital, Sapporo, Japan.

出版信息

Nucl Med Commun. 2002 Jul;23(7):639-43. doi: 10.1097/00006231-200207000-00008.

DOI:10.1097/00006231-200207000-00008
PMID:12089486
Abstract

A scintillator-photodiode camera is able to acquire single photon emission computed tomography (SPECT) images by using a rotating chair system. We validated the left ventricular (LV) parameters of this camera system utilizing a dynamic myocardial phantom. Gated myocardial SPECT of a dynamic myocardial phantom (Hokkaido University type; end diastolic volume (EDV), 143 ml; end systolic volume (ESV), 107 ml; ejection fraction (EF), 25%) was performed with this scintillation camera. LV parameters were calculated using pre-installed software (Mirage Myocardial Perfusion SPECT) (study 1) and the other software (QGS; Cedars-Sinai) (study 2). For comparison, SPECT from a traditional Anger camera were processed by the QGS software (study 3). The estimated volumes were similar among the three studies (EDV, 110+/-8 ml in study 1, 112+/-2 ml in study 2 and 111+/-1 ml in study 3; ESV, 86+/-8 ml in study 1, 93+/-4 ml in study 2 and 91+/-2 ml in study 3). The estimated EFs were 23+/-3%, 17+/-2%, and 18+/-1%, respectively. The calculated volume within each study was underestimated by approximately the same degree. However, each estimated EF value for each study was close to the actual value. The estimated LV function using the scintillator-photodiode camera system may be considered as a suitable alternative to the traditional Anger camera system.

摘要

闪烁体-光电二极管相机能够通过使用旋转椅系统获取单光子发射计算机断层扫描(SPECT)图像。我们利用动态心肌模型验证了该相机系统的左心室(LV)参数。使用该闪烁相机对动态心肌模型(北海道大学型;舒张末期容积(EDV),143 ml;收缩末期容积(ESV),107 ml;射血分数(EF),25%)进行门控心肌SPECT检查。LV参数使用预安装软件(Mirage心肌灌注SPECT)(研究1)和其他软件(QGS;雪松西奈医疗中心)(研究2)进行计算。为作比较,传统安格相机的SPECT图像由QGS软件进行处理(研究3)。三项研究中估计的容积相似(研究1中EDV为110±8 ml,研究2中为112±2 ml,研究3中为111±1 ml;研究1中ESV为86±8 ml,研究2中为93±4 ml,研究3中为91±2 ml)。估计的EF分别为23±3%、17±2%和18±1%。每项研究中计算出的容积均被低估了大致相同的程度。然而,每项研究中估计的EF值均接近实际值。使用闪烁体-光电二极管相机系统估计的LV功能可被视为传统安格相机系统的合适替代方案。

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引用本文的文献

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