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18F-氟代脱氧葡萄糖正电子发射断层显像在一例胃癌多发骨转移病例中的应用

FDG-PET in a case of multiple bone metastases of gastric cancer.

作者信息

Nakai Takako, Okuyama Chio, Kubota Takao, Ushijima Yo, Nishimura Tsunehiko

机构信息

Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine.

出版信息

Ann Nucl Med. 2005 Feb;19(1):51-4. doi: 10.1007/BF02986336.

Abstract

F-18 2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) is useful for surveys to detect bone metastasis because of its greater specificity than bone scintigraphy. However, FDG-PET is also known to yield false-positive results in acute fractures and inflammatory lesions, and distinguishing between benign and malignant lesions is difficult, even when semiquantitative methods are used. We report a case of multiple bone metastases of gastric cancer. One of the bone lesions that was positive for FDG uptake was benign, suggesting that FDG-PET can yield false-positive results.

摘要

F-18 2-氟-2-脱氧-D-葡萄糖(FDG)正电子发射断层扫描(PET)因其比骨闪烁显像具有更高的特异性,在检测骨转移的筛查中很有用。然而,FDG-PET在急性骨折和炎性病变中也会产生假阳性结果,即使使用半定量方法,区分良性和恶性病变也很困难。我们报告一例胃癌多发骨转移病例。其中一个FDG摄取呈阳性的骨病变是良性的,这表明FDG-PET可能会产生假阳性结果。

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