来自威氏鼠麴草的克罗烷二萜类化合物。

Clerodane diterpenoids from Pulicaria wightiana.

作者信息

Das Biswanath, Ravinder Reddy M, Ramu R, Ravindranath N, Harish H, Ramakrishna K V S, Koteswar Rao Y, Harakishore K, Murthy U S N

机构信息

Indian Institute of Chemical Technology, Organic Chemistry-1, Tarnaka, Hyderabad 500 007, India.

出版信息

Phytochemistry. 2005 Mar;66(6):633-8. doi: 10.1016/j.phytochem.2005.02.004.

DOI:10.1016/j.phytochem.2005.02.004

PMID:15771881

Abstract

Five clerodane diterpenoids have been isolated from the aerial parts of Pulicaria wightiana along with 3'5,6-trihydroxy-3,4',7-trimethoxyflavone and 2-methyl-5-hydroxy-chroman-4-one. The structures and stereochemistry of the compounds were established from spectral (mainly 1D and 2D NMR) studies. The last two compounds were not reported earlier from this plant. The antibacterial activity of the diterpenoids were studied.

摘要

从威氏旋覆花的地上部分分离出了五种克罗烷二萜类化合物，以及3',5,6-三羟基-3,4',7-三甲氧基黄酮和2-甲基-5-羟基色满-4-酮。通过光谱（主要是一维和二维核磁共振）研究确定了这些化合物的结构和立体化学。后两种化合物此前未从该植物中报道过。对二萜类化合物的抗菌活性进行了研究。