Edelman D A
Medical Research Consultants, Groton, CT 06340.
Int Arch Occup Environ Health. 1992;63(7):469-75. doi: 10.1007/BF00572113.
The risk of urogenital cancer to workers exposed to asbestos was evaluated using the results of published studies. The pooled standardized mortality ratios (SMRs), based on the results of cohort studies, were significantly increased (P less than or equal to 0.05) for ovarian and kidney cancer in North American studies but not in other studies. Part of these increases probably is due to the use of inappropriate comparison populations and the failure to take into account risk factors associated with urogenital cancer. Other types of studies generally did not indicate that exposure to asbestos increases the risk of urogenital cancer. Generally, there is insufficient information to show that urogenital cancers are caused by occupational exposure to asbestos.
利用已发表研究的结果评估了接触石棉的工人患泌尿生殖系统癌症的风险。基于队列研究结果的汇总标准化死亡比率(SMRs),在北美研究中卵巢癌和肾癌显著升高(P小于或等于0.05),但在其他研究中并非如此。这些升高部分可能归因于使用了不恰当的对照人群,以及未考虑与泌尿生殖系统癌症相关的风险因素。其他类型的研究一般未表明接触石棉会增加泌尿生殖系统癌症的风险。总体而言,没有足够的信息表明泌尿生殖系统癌症是由职业性接触石棉所致。