Forrester A W, Lipsey J R, Teitelbaum M L, DePaulo J R, Andrzejewski P L
Johns Hopkins University.
Int J Psychiatry Med. 1992;22(1):33-46. doi: 10.2190/CJ9D-32C2-8CM7-FT3D.
Although many investigators have studied mood disorders following myocardial infarction, the prevalence, severity, and persistence of depression have been disputed, and standard rating scales and criteria for depressive disorders have infrequently been utilized. The authors' goal was to determine how frequently depressive disorders occur after myocardial infarction, and to investigate predisposing factors for such disorders.
Structured clinical interviews were administered to 129 inpatients within ten days of myocardial infarction. Patients were also evaluated using standardized rating scales for depression, social function, cognition, and physical impairment. DSM-III diagnoses were derived from the structured interview.
Major depressive syndromes were present in 19 percent (n = 25) of the patients and were associated with prior history of mood disorder, female sex, large infarcts, and functional physical impairment.
Major depression is common in the acute post-myocardial infarction period. Such disorders confer significant psychiatric morbidity and, if sustained, require psychiatric intervention.
尽管许多研究人员对心肌梗死后的情绪障碍进行了研究，但抑郁症的患病率、严重程度和持续时间一直存在争议，且很少使用抑郁障碍的标准评定量表和标准。作者的目的是确定心肌梗死后抑郁障碍的发生频率，并调查此类障碍的诱发因素。
在心肌梗死后十天内，对129名住院患者进行了结构化临床访谈。还使用抑郁、社会功能、认知和身体损伤的标准化评定量表对患者进行了评估。DSM-III诊断源自结构化访谈。
19%（n = 25）的患者存在重度抑郁综合征，且与既往情绪障碍史、女性、大面积梗死和功能性身体损伤有关。
重度抑郁在急性心肌梗死后时期很常见。此类障碍会导致显著的精神疾病发病率，若持续存在，则需要精神科干预。
