Gonzalez M B, Snyderman T B, Colket J T, Arias R M, Jiang J W, O'Connor C M, Krishnan K R
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.
Depression. 1996;4(2):57-62. doi: 10.1002/(SICI)1522-7162(1996)4:2<57::AID-DEPR3>3.0.CO;2-C.
Depression is more prevalent in patients with coronary artery disease (CAD) than in the general elderly population. Although CAD patients with depression have higher mortality rates, depression is often not recognized and treated in these patients. We administered structured psychiatric diagnostic interviews to 99 inpatients with CAD and diagnosed 23% with a major depressive episode (MDE) by DSM-IV criteria. Severity of medical illness and family history of psychopathology were indicators for increased risk for MDE. These findings may facilitate the recognition of CAD patients at greater risk for MDE.
抑郁症在冠心病（CAD）患者中比在一般老年人群中更为普遍。尽管患有抑郁症的CAD患者死亡率更高，但这些患者中的抑郁症往往未被识别和治疗。我们对99名CAD住院患者进行了结构化的精神科诊断访谈，并根据《精神疾病诊断与统计手册》第四版（DSM-IV）标准诊断出23%的患者患有重度抑郁发作（MDE）。疾病严重程度和精神病理学家族史是MDE风险增加的指标。这些发现可能有助于识别MDE风险更高的CAD患者。
