Nacro B, Dao B, Dahourou H, Hien F, Charpentier-Gautier L, Meda N, Van de Perre P, Cartoux M, Mandelbrot L, Dabis F
Service de Pédiatrie C.H.N.S.S, BP 676 Bobo-Dioulasso, Burkina Faso.
Dakar Med. 2000;45(2):188-90.
The aim of this study was to evaluate the prevalence rate and the risk factors for the carriage of hepatitis B markers in pregnant women in Bobo Dioulasso, Burkina Faso. Out of 917 pregnant women recruited during antenatal care, 98 (10.7%) were HBs antigen positive. Among these ones, 18.2% carded HBe antigen, 66.7% antiHBe antibodies and 95.6% antiHBc antibodies. Two risk factors were identified: maternal age of 23 and 28 (RR = 2.33, chi2 =12.21, p = 0.005) and widowage (Fisher test RR = 6.43, p = 0.0016). This high prevalence of HBs antigen calls for systematic screening for hepatitis B during antenatal care along with an immunization policy toward women of reproductive age and newborns.
本研究旨在评估布基纳法索博博迪乌拉索孕妇乙肝标志物携带率及其危险因素。在产前检查期间招募的917名孕妇中,98名(10.7%)乙肝表面抗原呈阳性。其中,18.2%携带乙肝e抗原,66.7%携带乙肝e抗体,95.6%携带乙肝核心抗体。确定了两个危险因素:母亲年龄为23岁和28岁(相对危险度=2.33,卡方=12.21,p=0.005)以及丧偶(费舍尔检验相对危险度=6.43,p=0.0016)。乙肝表面抗原的高携带率要求在产前检查期间对乙肝进行系统筛查,并针对育龄妇女和新生儿制定免疫政策。