Routh Jonathan C, Lischer Garrett H, Leibovich Bradley C
Department of Urology, Mayo Clinic, Rochester, Minnesota 55901, USA.
Urology. 2005 Mar;65(3):591. doi: 10.1016/j.urology.2004.09.008.
Nocardia asteroides complex is a rare human pathogen chiefly affecting immunosuppressed patients. We present the sixth case of epididymo-orchitis attributable to this organism. A 78-year-old man presented to the Mayo Clinic with fever and weight loss after being treated with cyclophosphamide and prednisone for an immune-mediated vasculitis. He was found to have a testicular abscess, and orchiectomy was performed. N. asteroides complex was identified on the wound cultures. Sulfa therapy was begun. In previous case reports, this condition carried a 50% mortality rate. Patients who survive seemed to benefit from aggressive surgical debridement and long-term sulfa therapy.
星形诺卡菌复合体是一种罕见的人类病原体，主要影响免疫抑制患者。我们报告了第六例由该病原体引起的附睾睾丸炎。一名78岁男性因免疫介导性血管炎接受环磷酰胺和泼尼松治疗后，出现发热和体重减轻，就诊于梅奥诊所。他被发现患有睾丸脓肿，并接受了睾丸切除术。伤口培养物中鉴定出星形诺卡菌复合体。开始使用磺胺类药物治疗。在之前的病例报告中，这种疾病的死亡率为50%。存活下来的患者似乎受益于积极的手术清创和长期的磺胺类药物治疗。
