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[布鲁氏菌性附睾炎伴脓肿]

[[Brucellar orchiepididymitis with abscess].

作者信息

González Sánchez F J, Encinas Gaspar M B, Napal Lecumberri S, Rajab R

机构信息

Servicio de Radiodiagnóstico, Hospital Santos Reyes, Aranda de Duero, Burgos, España.

出版信息

Arch Esp Urol. 1997 Apr;50(3):289-92.

PMID:9395418
Abstract

OBJECTIVE

To emphasize the need to consider Brucella infection in patients presenting with acute scrotum of a possible inflammatory etiology, in endemic areas, as in some Spanish regions. The abscess forming type, although rare, should be considered. One such case is described herein and the literature briefly reviewed.

METHODS

A male patient consulted for subacute inflammation and left testicular pain. He had systemic brucellosis four months earlier that had completely remitted following specific therapy. The patient had a physical examination, analytical, blood and urine analyses, specific serological tests and testicular ultrasound evaluation.

RESULTS

Physical examination disclosed left testicular pain and inflammation suggesting epididimo-orchitis. The laboratory findings were normal except for high titles against Brucella. Ultrasound disclosed diffuse enlargement of the left testis with several well-defined hypoechoic areas. The foregoing data suggested abscess forming orchitis, although a neoplasm could not be discarded. Empirical antibiotic therapy was instituted initially and specific therapy for Brucella was administered subsequently, but unilateral orchidectomy was decided because of the poor response to therapy. Histopathological analysis of the surgical specimen disclosed acute abscess forming epididimo-orchitis with multifocal chronic granulomatous involvement.

CONCLUSION

Brucella epididimo-orchitis must be considered when making the differential diagnosis in acute inflammatory scrotum, particularly in endemic areas, even in the absence of suggestive clinical and/or US findings. Necrotizing orchitis is a rare form of Brucella infection which must be distinguished from necrotizing involvement arising from other pathogens (TB or Salmonella). Above all, this condition must be distinguished from a tumor.

摘要

目的

强调在某些西班牙地区等布鲁氏菌病流行地区,对于出现可能由炎症引起的急性阴囊炎的患者,需要考虑布鲁氏菌感染。应考虑脓肿形成型,尽管这种情况罕见。本文描述了这样一个病例并简要回顾了相关文献。

方法

一名男性患者因亚急性炎症和左侧睾丸疼痛前来就诊。他四个月前患有全身性布鲁氏菌病,经特异性治疗后已完全缓解。对该患者进行了体格检查、分析检查、血液和尿液分析、特异性血清学检测以及睾丸超声评估。

结果

体格检查发现左侧睾丸疼痛和炎症,提示附睾炎或睾丸炎。除了针对布鲁氏菌的高滴度抗体外,实验室检查结果均正常。超声显示左侧睾丸弥漫性肿大,有几个边界清晰的低回声区。上述数据提示脓肿形成性睾丸炎,尽管不能排除肿瘤。最初给予经验性抗生素治疗,随后给予布鲁氏菌特异性治疗,但由于治疗反应不佳决定进行单侧睾丸切除术。手术标本的组织病理学分析显示急性脓肿形成性附睾炎伴多灶性慢性肉芽肿性病变。

结论

在对急性炎症性阴囊进行鉴别诊断时,必须考虑布鲁氏菌附睾炎或睾丸炎,特别是在流行地区,即使没有提示性的临床和/或超声检查结果。坏死性睾丸炎是布鲁氏菌感染的一种罕见形式,必须与其他病原体(结核或沙门氏菌)引起的坏死性病变相鉴别。最重要的是,这种情况必须与肿瘤相鉴别。

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