Vaughn Matthew W, Martienssen Robert A
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Mol Cell. 2005 Mar 18;17(6):754-6. doi: 10.1016/j.molcel.2005.03.003.
A paradox of RNA-directed transcriptional silencing is that low-level transcription through the silenced locus is observed and may help maintain the silenced state. Discovery of a plant-specific RNA polymerase that directs heterochromatic silencing helps to resolve this issue.
RNA 介导的转录沉默的一个悖论是,人们观察到通过沉默位点的低水平转录,且这种转录可能有助于维持沉默状态。一种指导异染色质沉默的植物特异性 RNA 聚合酶的发现有助于解决这一问题。