Feuerer Markus, Benoist Christophe, Mathis Diane
Section on Immunology and Immunogenetics, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
Immunity. 2005 Mar;22(3):271-2. doi: 10.1016/j.immuni.2005.03.002.
Identification of the transcription factor Foxp3 as a "master regulator" of regulatory T (T(R)) cells was a major discovery. A new study by Fontenot et al. (2005), reported in this issue of Immunity, provides novel insights into T(R) cell biology by tracking their behavior in mice expressing a GFP-Foxp3 fusion-protein reporter.
