Suppr超能文献

[老年人的维生素B12、叶酸与心理功能]

[Vitamin B12, folic acid and mental function in the elderly].

作者信息

Meertens Lesbia, Solano Liseti

机构信息

Centro de Investigaciones en Nutrición, Facultad de Ciencias de la Salud, Universidad de Carabobo, Valencia, Venezuela.

出版信息

Invest Clin. 2005 Mar;46(1):53-63.

Abstract

Elderly people is a vulnerable population group to specific nutrient deficiencies as vitamin B12 and folic acid, which are closely related to mental functions deterioration, especially of cognitive functions. This study was aimed to measure B12 vitamin and folic acid indicators and to establish relationships to mental function. 53 elderly, older than 60 years, living in a geriatric home were assessed. The dietary intake was evaluated by the direct weighed method, serum B12 vitamin and folic acid by radioimmunoanalysis and mental function by Foltein's mini-mental test. Dietary intake for Vit B12 was adequate and deficient for folic acid while serum levels were within normal range. Vitamin B12 levels were at marginal or deficiency values in 26,4% of the elderly and folic acid deficiency was present in 43.4%. 49% of the elderly had mental function alterations and B12 vitamin levels were significantly lower in this group. A positive association between age and mental function (elderly below 80 years had lower risk of mental impairment) and between serum B12 and mental function were found. Elderly were at risk of deficiency for both vitamins and age and mental function were associated to this risk. Further evaluation including other nutrients should be performed.

摘要

老年人是特定营养素缺乏的脆弱人群,如维生素B12和叶酸,这些营养素与精神功能衰退,尤其是认知功能衰退密切相关。本研究旨在测量维生素B12和叶酸指标,并建立与精神功能的关系。对居住在养老院的53名60岁以上的老年人进行了评估。通过直接称重法评估饮食摄入量,通过放射免疫分析评估血清维生素B12和叶酸水平,通过福尔斯坦简易精神状态检查表评估精神功能。维生素B12的饮食摄入量充足,叶酸摄入量不足,而血清水平在正常范围内。26.4%的老年人维生素B12水平处于边缘或缺乏值,43.4%的老年人存在叶酸缺乏。49%的老年人有精神功能改变,该组维生素B12水平显著较低。发现年龄与精神功能之间(80岁以下老年人精神损害风险较低)以及血清维生素B12与精神功能之间呈正相关。老年人有两种维生素缺乏的风险,年龄和精神功能与这种风险相关。应进行包括其他营养素在内的进一步评估。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验