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睾丸癌与海湾战争服役有关吗?基于海湾战争时期退伍军人和癌症登记处的一项试点人群研究的证据。

Is testicular cancer related to Gulf War deployment? Evidence from a pilot population-based study of Gulf War era veterans and cancer registries.

作者信息

Levine Paul H, Young Heather A, Simmens Samuel J, Rentz Danielle, Kofie Vincent E, Mahan Clare M, Kang Han K

机构信息

Department of Epidemiology and Biostatistics, School of Public Health and Health Services, George Washington University, Ross Hall, Suite 118, 2300 I Street NW, Washington, DC 20037, USA.

出版信息

Mil Med. 2005 Feb;170(2):149-53.

PMID:15782837
Abstract

The possible relationship between military deployment and the subsequent increase in cancer rates has been prominent since the Vietnam War. The objective of this study was to investigate whether any form of cancer was increased among veterans deployed to the Persian Gulf in the 1991 conflict. This study matched data from central cancer registries in the District of Columbia and New Jersey with the records for 1.4 million Gulf War era veterans, i.e., 621,902 veterans who arrived in the Persian Gulf before March 1, 1991, and 746,248 non-Gulf veterans. Using a proportional incidence ratio, testicular cancer was found to be the only significantly increased malignancy among deployed Persian Gulf War veterans. The increase became apparent 2 to 3 years after the Persian Gulf War and peaked 4 to 5 years afterward. Our data and those of investigators studying Vietnam veterans suggest that testicular cancer may be related to military deployment.

摘要

自越南战争以来,军事部署与随后癌症发病率上升之间的可能关系就备受关注。本研究的目的是调查在1991年冲突中被部署到波斯湾的退伍军人中,是否有任何一种癌症的发病率有所增加。本研究将哥伦比亚特区和新泽西州中央癌症登记处的数据与140万海湾战争时期退伍军人的记录进行了匹配,即1991年3月1日前抵达波斯湾的621902名退伍军人,以及746248名非海湾退伍军人。使用比例发病率,发现睾丸癌是被部署的海湾战争退伍军人中唯一显著增加的恶性肿瘤。这种增加在海湾战争后2至3年变得明显,并在之后4至5年达到峰值。我们的数据以及研究越南退伍军人的调查人员的数据表明,睾丸癌可能与军事部署有关。

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