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结直肠癌患者的术后感染

Postoperative infections in colorectal cancer patients.

作者信息

Horzic Matija, Kopljar Mario

机构信息

Department of Surgery, University Hospital Dubrava, Zagreb, Croatia.

出版信息

Hepatogastroenterology. 2005 Jan-Feb;52(61):101-4.

Abstract

BACKGROUND/AIMS: Colorectal surgery is associated with some of the highest rates of infective complications, and especially surgical site infections. It has recently been reported that postoperative infection in colorectal cancer surgery increases the risk of recurrence. The aim of this study was to analyze factors associated with the occurrence of postoperative infections in patients with colorectal cancer.

METHODOLOGY

A total of 81 patients operated for colorectal cancer was included. Patients' characteristics and postoperative course were recorded and analyzed.

RESULTS

Patients with tumors located in the rectum had significantly higher rate of postoperative infectious complications compared to patients with tumors located in the colon (p=0.002). In a logistic regression model, among all evaluated predictors, only preoperative hemoglobin concentration was found to be an independent significant predictor of postoperative infection (p=0.01).

CONCLUSIONS

Preoperative anemia was found to be significant independent predictor of postoperative infection. Meticulous surgical technique with minimal blood loss is an important means of reduction of postoperative infections in colorectal surgery.

摘要

背景/目的:结直肠手术的感染并发症发生率极高,尤其是手术部位感染。最近有报道称,结直肠癌手术的术后感染会增加复发风险。本研究的目的是分析结直肠癌患者术后感染发生的相关因素。

方法

共纳入81例行结直肠癌手术的患者。记录并分析患者的特征及术后病程。

结果

与肿瘤位于结肠的患者相比,肿瘤位于直肠的患者术后感染并发症发生率显著更高(p = 0.002)。在逻辑回归模型中,在所有评估的预测因素中,仅术前血红蛋白浓度被发现是术后感染的独立显著预测因素(p = 0.01)。

结论

术前贫血被发现是术后感染的显著独立预测因素。采用精细的手术技术并尽量减少失血是降低结直肠手术术后感染的重要手段。

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