Skenderis B S, Rodriguez-Bigas M, Weber T K, Petrelli N J
Division of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA.
Cancer Invest. 1999;17(2):102-9.
In an effort to lower healthcare costs, this study was undertaken to evaluate the utility of routine postoperative (PO) laboratory studies and determine whether abnormalities alter patient (PT) care. This was a retrospective review of 105 PTs undergoing elective curative resection for colorectal cancer. A serum electrolyte and liver panel and a hematologic panel were drawn in all PTs. OF 8749 total laboratory values obtained, 5894 (67%) were normal. Two of these (0.03%) elicited a therapeutic intervention. Of the 2004 values that were low (23%), 103 (5.1%) elicited a therapeutic response. Of the 851 that were high (10%), 21 (2.5%) elicited a therapeutic response. Of 2089 preoperative laboratory values, 252 (12%) were abnormal, but in only 15 incidences in 9 PTs was any action taken. Three PTs required potassium supplementation and 6 PTs were transfused packed red blood cells before surgery. In the PO period 2603 laboratory values of 6660 obtained (39%) were abnormal. Of these, 735 (28%) were high and 1868 (72%) were low. Twenty of 735 (27%) high values triggered a therapeutic response that most commonly required administration of insulin for elevated serum glucose in 17 of 197 occasions in five diabetic PTs. On three occasions potassium was removed from intravenous fluids. Five of 275 (1.8%) low calcium values were treated in five patients. Potassium was replaced in 17 of 32 occasions in 14 patients where it was low. In this group of PTs, PO serum potassium, hemoglobin levels, and serum glucose in diabetics were the only values important in making therapeutic decisions. If laboratory studies can be streamlined into only those necessary, substantial savings in health care will be seen without sacrificing quality medical care.
为降低医疗成本,本研究旨在评估术后常规实验室检查的效用,并确定异常结果是否会改变患者的治疗方案。这是一项对105例接受择期结直肠癌根治性切除术患者的回顾性研究。所有患者均进行了血清电解质、肝功能检查和血液学检查。在总共获得的8749项实验室检查结果中,5894项(67%)正常。其中两项(0.03%)引发了治疗干预。在2004项偏低的结果中(23%),103项(5.1%)引发了治疗反应。在851项偏高的结果中(10%),21项(2.5%)引发了治疗反应。在2089项术前实验室检查结果中,252项(12%)异常,但仅在9例患者的15次检查中采取了任何措施。3例患者需要补充钾,6例患者在手术前输注了浓缩红细胞。在术后期间,6660项检查结果中的2603项(39%)异常。其中,735项(28%)偏高,1868项(72%)偏低。735项偏高结果中的20项(27%)引发了治疗反应,最常见的是在5例糖尿病患者的197次检查中有17次因血糖升高需要注射胰岛素。有3次从静脉输液中去除了钾。275项偏低的钙值中有5项(1.8%)在5例患者中得到治疗。14例患者中有17次(32次中的)血钾偏低时进行了补钾。在这组患者中,术后血清钾、血红蛋白水平以及糖尿病患者的血糖是做出治疗决策时唯一重要的值。如果实验室检查能够简化为仅进行必要的检查,在不牺牲优质医疗护理的情况下,将大幅节省医疗费用。